Emerging Technologies to Improve Capsaicin Delivery and its Therapeutic Efficacy

Capsaicin, a pungent alkaloid of chili pepper (Capsicum annuum) is responsible for the “hot and spicy” taste of chili. Also, Capsaicin is a pharmaceutical agent with broad therapeutic applications in controlling different diseases like diabetes, obesity, cancer, pain, and other inflammatory diseases. Capsaicin therapeutic effect is dependent on various factors like the concentration of capsaicin, delivery to different cell types, route of administration, and their metabolism. Improvement in the delivery of capsaicin will increase its therapeutic efficacy. Recent advancement in various technologies had provided numerous strategies to deliver capsaicin. This chapter outlines different strategies for using multiple new materials, formulations for the capsaicin delivery and improve their therapeutic efficacy as well their advantages and disadvantages