Hartley and Potts (2014) argue that cultural science represents a new theoretical and methodological approach to the study of cultural structure, dynamics and use. We explain how this differs from the extant analytic frameworks of cultural studies, both as a research program and as a policy platform. The central idea is to reconceptualize what culture is, through a reinterpretation of what culture does. We argue that the semiotic productivity of culture makes groups - which we call demes - and demes make knowledge (what we call the externalism hypothesis); and the interaction of demes makes newness - new knowledge. Cultural science, then, is a new model of the cultural processes involved in socio-economic evolution and innovation of knowled...