Fast kVp-Switching Dual Energy CT for PET Attenuation Correction

X-ray CT images are used routinely for attenuation correction in PET/CT systems. However, conventional CT-based attenuation correction (CTAC) can be inaccurate in regions containing iodine contrast agent. Dual-energy (DE) CT has the potential to improve the accuracy of attenuation correction in PET, but conventional DECT can suffer from motion artifacts. Recent X-ray CT systems can collect DE sinograms by rapidly switching the X-ray tube voltage between two levels for alternate projection views, reducing motion artifacts. The goal of this work is to study statistical methods for image reconstruction from both fast kVp-switching DE scans and from conventional dual-rotate DE scans in the context of CTAC for PET.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/86003/1/Fessler244.pd