Autism in Down's syndrome: family history correlates

Although the association of autism with Down's syndrome is said to be uncommon, several reports have described the co-occurrence of the two disorders. This report describes three additional cases of Down's syndrome with autism. In all the patients, a history suggestive of the broader phenotype of autism was obtained In parents. This suggests that familial factors SFtecific to autism may play an important role even when autism complicates a known medical condition such as Down's syndrome.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74250/1/j.1365-2788.1997.tb00681.x.pd