Add to ORKGExperimental animal models are essential to obtain basic knowledge of the underlying biological mechanisms in human diseases. Here, we review major contributions to biomedical research and discoveries that were obtained in the mouse model by using forward genetics approaches and that provided key insights into the biology of human diseases and paved the way for the development of novel therapeutic approaches
Understanding the genetic aetiology of loci associated with a disease is crucial for developing prev...
The laboratory mouse is an ideal model organism for studying disease because it is physiologically s...
Ongoing studies in many species seek to understand the origins, architecture and consequences of phe...
peer reviewedExperimental animal models are essential to obtain basic knowledge of the underlying bi...
Experimental animal models are essential to obtain basic knowledge of the underlying biological mech...
Mice have become the mammalian model of choice for the application of genetics in biomedical researc...
A recent publication questions the suitability of mice as a model for the human inflammatory respons...
The mouse is an ideal model organism for studies of human disease, because mouse is physiologically ...
The mouse has many advantages over human beings for the study of genetics, including the unique prop...
Small differences in our genome distinguish us from each other. Although diversity is a good thing, ...
Mouse models have been instrumental in understanding human disease biology and proposing possible ne...
Click on the link below to access the article (may not be free).A valuable approach to investigating...
This dissertation is the culmination of my graduate studies in the laboratory of Jake Lusis at UCLA....
Analyses of the human genome have proven extremely successful in identifying changes that contribute...
The mouse is the leading organism for disease research. A rich resource of genetic variation occurs ...
Understanding the genetic aetiology of loci associated with a disease is crucial for developing prev...
The laboratory mouse is an ideal model organism for studying disease because it is physiologically s...
Ongoing studies in many species seek to understand the origins, architecture and consequences of phe...
peer reviewedExperimental animal models are essential to obtain basic knowledge of the underlying bi...
Experimental animal models are essential to obtain basic knowledge of the underlying biological mech...
Mice have become the mammalian model of choice for the application of genetics in biomedical researc...
A recent publication questions the suitability of mice as a model for the human inflammatory respons...
The mouse is an ideal model organism for studies of human disease, because mouse is physiologically ...
The mouse has many advantages over human beings for the study of genetics, including the unique prop...
Small differences in our genome distinguish us from each other. Although diversity is a good thing, ...
Mouse models have been instrumental in understanding human disease biology and proposing possible ne...
Click on the link below to access the article (may not be free).A valuable approach to investigating...
This dissertation is the culmination of my graduate studies in the laboratory of Jake Lusis at UCLA....
Analyses of the human genome have proven extremely successful in identifying changes that contribute...
The mouse is the leading organism for disease research. A rich resource of genetic variation occurs ...
Understanding the genetic aetiology of loci associated with a disease is crucial for developing prev...
The laboratory mouse is an ideal model organism for studying disease because it is physiologically s...
Ongoing studies in many species seek to understand the origins, architecture and consequences of phe...