The modification of membranes by polyelectrolytes via the Layer-by-Layer technique is an attractive method to obtain nanofiltration membranes. We prepare such membranes by alternatively coating a polycation (poly(diallyldimethylammonium chloride) (PDADAMAC)) and a polyanion (poly(styrene sulfonate) (PSS)) on a porous support. Depending on the coating conditions, hollow fiber membranes with rejections of up to 71% NaCl and 96% Na2SO4 are obtained. Moreover, we demonstrate that the final membrane properties can be easily controlled by variation of the ionic strength of the coating solution, the number of layers and the choice of terminating polyelectrolyte layer. Coating at higher salt concentrations results in thicker multilayers that are mo...