The effects of CRF antagonists, antalarmin, CP154,526, LWH234, and R121919, in the forced swim test and on swim-induced increases in adrenocorticotropin in rats
- Houshyar, Hani
- Woods, James H.
- Wood, Susan K.
- Rice, Kenner C.
- Hsin, Ling-Wei
- Jutkiewicz, Emily M.
Publication date
July 2005
DOI Publisher
Springer Science and Business Media LLC ISSN
0033-3158 Journal
Psychopharmacology Citation count (estimate)
66Abstract
Exposure to extreme stress has been suggested to produce long-term, detrimental alterations in the hypothalamic–pituitary–adrenal (HPA) axis leading to the development of mental disorders such as depression. Therefore, compounds that block the effects of stress hormones were investigated as potential therapeutics for depression.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46365/1/213_2005_Article_2164.pd
Add to ORKG