Analysis of normal and mutant forms of human adenosine deaminase — A review

A deficiency of the enzyme adenosine deaminase is associated with an autosomal recessive form of severe combined immunodeficiency disease in man. The molecular forms of the normal human enzyme have now been well characterized in an effort to better understand the nature of the enzyme defect in affected patients.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45343/1/11010_2004_Article_BF00220303.pd