Overexpression of caveolin-1 and -2 in cell lines and in human samples of inflammatory breast cancer

Marck, Eric A.
Golen, Kenneth L.
Vermeulen, Peter B.
Eynden, Gert G.
Laere, Steven J.
Auwera, Ilse
Merajver, Sofia D.
Dam, Peter
Dirix, Luc Y.

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Publication date

February 2006

DOI

10.1007/s10549-005-9002-1

Publisher

Springer Science and Business Media LLC

Journal

Breast Cancer Research and Treatment

Abstract

Inflammatory breast cancer (IBC) is the most aggressive form of locally advanced breast cancer (LABC). The IBC phenotype is characterized by an infiltrative growth pattern, increased (lymph)angiogenesis and the propensity to invade dermal lymphatics. In pancreatic cancer, interactions between caveolin-1 and RhoC GTPase, a key molecule in causing the IBC phenotype, regulate tumour cell motility and invasion. In this study we sought to investigate the role of caveolin-1 and -2 in IBC cell lines and in human IBC samples.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/44235/1/10549_2005_Article_9002.pd

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Overexpression of caveolin-1 and -2 in cell lines and in human samples of inflammatory breast cancer

Abstract

Extracted data

Overexpression of caveolin-1 and -2 in cell lines and in human samples of inflammatory breast cancer

Abstract

Extracted data

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