Liposomal Formulations of Inflammatory Bowel Disease Drugs: Local versus Systemic Drug Delivery in a Rat Model

Fleisher, David
Zhou, Simon Yuji
Zimmermann, Ellen M.
Kesisoglou, Filippos
Niemiec, Susan M.
Lee, Jordan Wing

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Publication date

August 2005

DOI

10.1007/s11095-005-5376-3

Publisher

Springer Science and Business Media LLC

ISSN

0724-8741

Journal

Pharmaceutical Research

Citation count (estimate)

Abstract

Based on adherence to intestinal mucosa, intralumenally administered liposomal formulations of 5-aminosalicylate (5-ASA) and 6-mercaptopurine (6-MP) were studied for their potential to enhance local drug delivery to intestinal tissue for the treatment of inflammatory bowel disease.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/41509/1/11095_2005_Article_5376.pd

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Liposomal Formulations of Inflammatory Bowel Disease Drugs: Local versus Systemic Drug Delivery in a Rat Model

Abstract

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Liposomal Formulations of Inflammatory Bowel Disease Drugs: Local versus Systemic Drug Delivery in a Rat Model

Abstract

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