Rheological Characterization of Topical Carbomer Gels Neutralized to Different pH

Purpose . The primary objective of this study is to perform detailed and extensive rheological characterization of rheology of carbomer (Carbopol) microgels formulated using a solvent system typically used in topical gel formulations. Solvents like glycerin and propylene glycol can alter rheology and drug delivery characteristics of topical gels owing to their different viscosities and due to the change in solvent-polymer and solvent-solvent interactions.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/41505/1/11095_2004_Article_489401.pd