A Multi-Institutional Phase II Trial of Preoperative Full-Dose Gemcitabine and Concurrent Radiation for Patients With Potentially Resectable Pancreatic Carcinoma

Multi-institutional phase I study of low-dose ultra-fractionated radiotherapy as a chemosensitizer for gemcitabine and erlotinib in patients with locally advanced or limited metastatic pancreatic cancer.

Konski, Andre
Meyer, Joshua E
Joiner, Michael
Hall, Michael J
Philip, Philip
Shields, Anthony
McSpadden, Erin
Choi, Minsig
Adaire, Beth
Duncan, Gail
Meropol, Neal J
Cescon, Terrence P
Cohen, Steven J

October 2014

PURPOSE: Gemcitabine (G) has been shown to sensitize pancreatic cancer to radiotherapy but requires ...

Phase III trial comparing initial chemoradiotherapy (intermittent cisplatin and infusional 5-FU) followed by gemcitabine vs gemcitabine alone in patients with locally advanced non metastatic pancreatic cancer. Preliminary results.

Chauffert, B.
Toledano, A.
Bonnetain, Franck
Triboulet, Jp
Bouche, O.
Rougier, P.
Bosset, Jf.
Aparicio, T.
Masskouri, F.
Bedenne, L.

June 2006

International audienceBackground: The GITSG studies have shown a greater survival after 5 FU-based c...

Unresectable pancreatic cancer: survival and secondary resections after chemoradiotherapy followed by gemcitabine compared to gemcitabine alone (SFRO/FFCD 2000-01 phase III trial).

Rougier, P.
Mornex, F.
Chauffert, B.
Ricard, F.
Mariette, C.
Bouche, O.
Bosset, Jf.
Aparicio, T.
Mineur, L.
Bonnetain, Franck
Mitry, E.
Bedenne, L.

June 2007

International audienceBackground: In patients (pts) with locally advanced non metastatic pancreatic ...

A multi‐institutional phase 2 study of neoadjuvant gemcitabine and oxaliplatin with radiation therapy in patients with pancreatic cancer

Kim, Edward J.
Ben‐josef, Edgar
Herman, Joseph M.
Bekaii‐saab, Tanios
Dawson, Laura A.
Griffith, Kent A.
Francis, Isaac R.
Greenson, Joel K.
Simeone, Diane M.
Lawrence, Theodore S.
Laheru, Daniel
Wolfgang, Christopher L.
Williams, Terence
Bloomston, Mark
Moore, Malcolm J.
Wei, Alice
Zalupski, Mark M.

August 2013

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/99090/1/cncr28117.pd

A Multi-Institutional Phase II Trial of Preoperative Full-Dose Gemcitabine and Concurrent Radiation for Patients With Potentially Resectable Pancreatic Carcinoma

Timothy J. Kinsella
Philip A. Philip
Cornelius J. Mcginn

December 2014

Background: We report the results of a multi-institutional phase II trial that used preop-erative fu...

Adjuvant gemcitabine alone versus gemcitabine-based chemoradiotherapy after curative resection for pancreatic cancer: a randomized EORTC-40013-22012/FFCD-9203/GERCOR phase II study.

Van Laethem, Jean*-Luc
Hammel, Pascal
Mornex, Francoise
Azria, David
Van Tienhoven, Geertjan
Vergauwe, Philippe
Peeters, Marc
Polus, Marc
Praet, Michel
Mauer, Murielle
Collette, Laurence
Budach, Volker
Lutz, Manfred
Van Cutsem, Eric
Haustermans, Karin

January 2010

PURPOSE: The role of adjuvant chemoradiotherapy (CRT) in resectable pancreatic cancer is still debat...

On the development of gemcitabine-based chemoradiotherapy regimens in pancreatic cancer

McGinn, Cornelius J.
Lawrence, Theodore S.
Zalupski, Mark M.

August 2002

The use of chemotherapy with concurrent radiation therapy remains a standard treatment option for pa...

A Phase II Trial of Gemcitabine, 5-Florouracil, and Radiation Therapy in Locally Advanced Non-Metastatic Pancreatic Adenocarcinoma: Cancer and Leukemia Group B (CALGB) 80003

Mamon, Harvey J.
Niedzwiecki, Donna
Hollis, Donna
Tan, Benjamin R.
Mayer, Robert J.
Tepper, Joel E.
Goldberg, Richard M.
Blackstock, A. William
Fuchs, Charles S.

January 2011

To assess the efficacy and safety of 5-fluorouracil (5FU) and gemcitabine administered concurrently ...

Adjuvant radiotherapy and chemoradiation with gemcitabine after R1 resection in patients with pancreatic adenocarcinoma

Habermehl, Daniel
Brecht, Ingo C.
Bergmann, Frank
Rieken, Stefan
Werner, Jens
Büchler, Markus W.
Springfeld, Christoph
Jaeger, Dirk
Debus, Jürgen
Combs, Stephanie E.

January 2015

Background: The purpose of the study was to evaluate the effect of radiation therapy and chemoradiat...

External Beam Radiotherapy Plus 24-Hour Continuous Infusion of Gemcitabine in Unresectable Pancreatic Carcinoma: Long-Term Results of a Phase II Study

Mattiucci, Gian C.
Valentini, Vincenzo
Ippolito, Edy
Alfieri, Sergio
Antinori, Armando
Crucitti, Antonio
D'Agostino, Giuseppe R.
Di Lullo, Liberato
Luzi, Stefano
Mantini, Giovanna
Smaniotto, Daniela
Doglietto, Gian B.
Cellini, Numa
MORGANTI, ALESSIO GIUSEPPE

January 2010

Purpose: To evaluate the efficacy of gemcitabine-based chemoradiation (CT-RT) in treating patients (...

Gemcitabine and Oxaliplatin With Radiation Therapy in Patients With Pancreatic Cancer

Malcolm J. Moore
Md Alice Wei
Mark M. Zalupski

September 2016

BACKGROUND: The purpose of this study was to evaluate preoperative treatment with full-dose gemcitab...

Adjuvant gemcitabine and concurrent radiation for patients with resected pancreatic cancer: a phase II study

Blackstock, A. W.
Mornex, F.
Partensky, C.
Descos, L.
Case, L. D.
Melin, S. A.
Levine, E. A.
Mishra, G.
Limentani, S. A.
Kachnic, L. A.
Tepper, J. E.

January 2006

The safety and efficacy of gemcitabine and concurrent radiation to the upper abdomen followed by wee...

Preoperative Gemcitabine and Cisplatin Followed by Gemcitabine-Based Chemoradiation for Resectable Adenocarcinoma of the Pancreatic Head

Varadhachary, Gauri
Wolff, Robert
Crane, Christopher
Sun, Charlotte
Lee, Jeffrey
Pisters, Peter
Vauthey, Jean-Nicolas
Abdalla, Eddie
Wang, Huamin
Staerkel, Gregg
Ross, William
Tamm, Eric
Bhosale, Priya
Krishnan, Sunil
Das, Prajnan
Ho, Linus
Xiong, Henry
Abbruzzese, James
Evans, Douglas

November 2015

Purpose We conducted a phase II trial of preoperative gemcitabine and cisplatin chemotherapy in addi...

Preoperative radiochemotherapy versus immediate surgery for resectable and borderline resectable pancreatic cancer (PREOPANC trial): study protocol for a multicentre randomized controlled trial

Versteijne, E.
Eijck, C.H. van
Punt, C.J.A.
Suker, M.
Zwinderman, A.H.
Dohmen, M.A.C.
Groothuis, K.B.
Busch, O.R.
Besselink, M.G.
Hingh, I.H. de
Tije, A.J. Ten
Patijn, G.A.
Bonsing, B.A.
Vos-Geelen, J.
Klaase, J.M.
Festen, S.
Boerma, D.
Erdmann, J.I.
Molenaar, I.Q.
Harst, E. van der
Kolk, M. van der
Rasch, C.R.
Tienhoven, G. van
et al.

January 2016

Contains fulltext : 168591.pdf (publisher's version ) (Open Access)BACKGROUND: Pan...

Original Article Phase II Study of Combination Chemotherapy with Gemcitabine and Cisplatin for Patients with Metastatic Pancreatic Cancer

Hideki Ueno
Takuji Okusaka
Masafumi Ikeda
Chigusa Morizane
Takashi Ogura
Atsushi Hagihara

January 2007

Objective: The objectives of this study were to evaluate the efficacy and toxicity of combi-nation c...

Multi-institutional phase I study of low-dose ultra-fractionated radiotherapy as a chemosensitizer for gemcitabine and erlotinib in patients with locally advanced or limited metastatic pancreatic cancer.

Konski, Andre
Meyer, Joshua E
Joiner, Michael
Hall, Michael J
Philip, Philip
Shields, Anthony
McSpadden, Erin
Choi, Minsig
Adaire, Beth
Duncan, Gail
Meropol, Neal J
Cescon, Terrence P
Cohen, Steven J

October 2014

PURPOSE: Gemcitabine (G) has been shown to sensitize pancreatic cancer to radiotherapy but requires ...

Phase III trial comparing initial chemoradiotherapy (intermittent cisplatin and infusional 5-FU) followed by gemcitabine vs gemcitabine alone in patients with locally advanced non metastatic pancreatic cancer. Preliminary results.

Chauffert, B.
Toledano, A.
Bonnetain, Franck
Triboulet, Jp
Bouche, O.
Rougier, P.
Bosset, Jf.
Aparicio, T.
Masskouri, F.
Bedenne, L.

June 2006

International audienceBackground: The GITSG studies have shown a greater survival after 5 FU-based c...

Unresectable pancreatic cancer: survival and secondary resections after chemoradiotherapy followed by gemcitabine compared to gemcitabine alone (SFRO/FFCD 2000-01 phase III trial).

Rougier, P.
Mornex, F.
Chauffert, B.
Ricard, F.
Mariette, C.
Bouche, O.
Bosset, Jf.
Aparicio, T.
Mineur, L.
Bonnetain, Franck
Mitry, E.
Bedenne, L.

June 2007

International audienceBackground: In patients (pts) with locally advanced non metastatic pancreatic ...

A multi‐institutional phase 2 study of neoadjuvant gemcitabine and oxaliplatin with radiation therapy in patients with pancreatic cancer

Kim, Edward J.
Ben‐josef, Edgar
Herman, Joseph M.
Bekaii‐saab, Tanios
Dawson, Laura A.
Griffith, Kent A.
Francis, Isaac R.
Greenson, Joel K.
Simeone, Diane M.
Lawrence, Theodore S.
Laheru, Daniel
Wolfgang, Christopher L.
Williams, Terence
Bloomston, Mark
Moore, Malcolm J.
Wei, Alice
Zalupski, Mark M.

August 2013

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/99090/1/cncr28117.pd

A Multi-Institutional Phase II Trial of Preoperative Full-Dose Gemcitabine and Concurrent Radiation for Patients With Potentially Resectable Pancreatic Carcinoma

Timothy J. Kinsella
Philip A. Philip
Cornelius J. Mcginn

December 2014

Background: We report the results of a multi-institutional phase II trial that used preop-erative fu...

Adjuvant gemcitabine alone versus gemcitabine-based chemoradiotherapy after curative resection for pancreatic cancer: a randomized EORTC-40013-22012/FFCD-9203/GERCOR phase II study.

Van Laethem, Jean*-Luc
Hammel, Pascal
Mornex, Francoise
Azria, David
Van Tienhoven, Geertjan
Vergauwe, Philippe
Peeters, Marc
Polus, Marc
Praet, Michel
Mauer, Murielle
Collette, Laurence
Budach, Volker
Lutz, Manfred
Van Cutsem, Eric
Haustermans, Karin

January 2010

PURPOSE: The role of adjuvant chemoradiotherapy (CRT) in resectable pancreatic cancer is still debat...

On the development of gemcitabine-based chemoradiotherapy regimens in pancreatic cancer

McGinn, Cornelius J.
Lawrence, Theodore S.
Zalupski, Mark M.

August 2002

The use of chemotherapy with concurrent radiation therapy remains a standard treatment option for pa...

A Phase II Trial of Gemcitabine, 5-Florouracil, and Radiation Therapy in Locally Advanced Non-Metastatic Pancreatic Adenocarcinoma: Cancer and Leukemia Group B (CALGB) 80003

Mamon, Harvey J.
Niedzwiecki, Donna
Hollis, Donna
Tan, Benjamin R.
Mayer, Robert J.
Tepper, Joel E.
Goldberg, Richard M.
Blackstock, A. William
Fuchs, Charles S.

January 2011

To assess the efficacy and safety of 5-fluorouracil (5FU) and gemcitabine administered concurrently ...

Adjuvant radiotherapy and chemoradiation with gemcitabine after R1 resection in patients with pancreatic adenocarcinoma

Habermehl, Daniel
Brecht, Ingo C.
Bergmann, Frank
Rieken, Stefan
Werner, Jens
Büchler, Markus W.
Springfeld, Christoph
Jaeger, Dirk
Debus, Jürgen
Combs, Stephanie E.

January 2015

Background: The purpose of the study was to evaluate the effect of radiation therapy and chemoradiat...

External Beam Radiotherapy Plus 24-Hour Continuous Infusion of Gemcitabine in Unresectable Pancreatic Carcinoma: Long-Term Results of a Phase II Study

Mattiucci, Gian C.
Valentini, Vincenzo
Ippolito, Edy
Alfieri, Sergio
Antinori, Armando
Crucitti, Antonio
D'Agostino, Giuseppe R.
Di Lullo, Liberato
Luzi, Stefano
Mantini, Giovanna
Smaniotto, Daniela
Doglietto, Gian B.
Cellini, Numa
MORGANTI, ALESSIO GIUSEPPE

January 2010

Purpose: To evaluate the efficacy of gemcitabine-based chemoradiation (CT-RT) in treating patients (...

Gemcitabine and Oxaliplatin With Radiation Therapy in Patients With Pancreatic Cancer

Malcolm J. Moore
Md Alice Wei
Mark M. Zalupski

September 2016

BACKGROUND: The purpose of this study was to evaluate preoperative treatment with full-dose gemcitab...

Adjuvant gemcitabine and concurrent radiation for patients with resected pancreatic cancer: a phase II study

Blackstock, A. W.
Mornex, F.
Partensky, C.
Descos, L.
Case, L. D.
Melin, S. A.
Levine, E. A.
Mishra, G.
Limentani, S. A.
Kachnic, L. A.
Tepper, J. E.

January 2006

The safety and efficacy of gemcitabine and concurrent radiation to the upper abdomen followed by wee...

Preoperative Gemcitabine and Cisplatin Followed by Gemcitabine-Based Chemoradiation for Resectable Adenocarcinoma of the Pancreatic Head

Varadhachary, Gauri
Wolff, Robert
Crane, Christopher
Sun, Charlotte
Lee, Jeffrey
Pisters, Peter
Vauthey, Jean-Nicolas
Abdalla, Eddie
Wang, Huamin
Staerkel, Gregg
Ross, William
Tamm, Eric
Bhosale, Priya
Krishnan, Sunil
Das, Prajnan
Ho, Linus
Xiong, Henry
Abbruzzese, James
Evans, Douglas

November 2015

Purpose We conducted a phase II trial of preoperative gemcitabine and cisplatin chemotherapy in addi...

Preoperative radiochemotherapy versus immediate surgery for resectable and borderline resectable pancreatic cancer (PREOPANC trial): study protocol for a multicentre randomized controlled trial

Versteijne, E.
Eijck, C.H. van
Punt, C.J.A.
Suker, M.
Zwinderman, A.H.
Dohmen, M.A.C.
Groothuis, K.B.
Busch, O.R.
Besselink, M.G.
Hingh, I.H. de
Tije, A.J. Ten
Patijn, G.A.
Bonsing, B.A.
Vos-Geelen, J.
Klaase, J.M.
Festen, S.
Boerma, D.
Erdmann, J.I.
Molenaar, I.Q.
Harst, E. van der
Kolk, M. van der
Rasch, C.R.
Tienhoven, G. van
et al.

January 2016

Contains fulltext : 168591.pdf (publisher's version ) (Open Access)BACKGROUND: Pan...

Original Article Phase II Study of Combination Chemotherapy with Gemcitabine and Cisplatin for Patients with Metastatic Pancreatic Cancer

Hideki Ueno
Takuji Okusaka
Masafumi Ikeda
Chigusa Morizane
Takashi Ogura
Atsushi Hagihara

January 2007

Objective: The objectives of this study were to evaluate the efficacy and toxicity of combi-nation c...

Multi-institutional phase I study of low-dose ultra-fractionated radiotherapy as a chemosensitizer for gemcitabine and erlotinib in patients with locally advanced or limited metastatic pancreatic cancer.

Konski, Andre
Meyer, Joshua E
Joiner, Michael
Hall, Michael J
Philip, Philip
Shields, Anthony
McSpadden, Erin
Choi, Minsig
Adaire, Beth
Duncan, Gail
Meropol, Neal J
Cescon, Terrence P
Cohen, Steven J

October 2014

PURPOSE: Gemcitabine (G) has been shown to sensitize pancreatic cancer to radiotherapy but requires ...

Phase III trial comparing initial chemoradiotherapy (intermittent cisplatin and infusional 5-FU) followed by gemcitabine vs gemcitabine alone in patients with locally advanced non metastatic pancreatic cancer. Preliminary results.

Chauffert, B.
Toledano, A.
Bonnetain, Franck
Triboulet, Jp
Bouche, O.
Rougier, P.
Bosset, Jf.
Aparicio, T.
Masskouri, F.
Bedenne, L.

June 2006

International audienceBackground: The GITSG studies have shown a greater survival after 5 FU-based c...

Unresectable pancreatic cancer: survival and secondary resections after chemoradiotherapy followed by gemcitabine compared to gemcitabine alone (SFRO/FFCD 2000-01 phase III trial).

Rougier, P.
Mornex, F.
Chauffert, B.
Ricard, F.
Mariette, C.
Bouche, O.
Bosset, Jf.
Aparicio, T.
Mineur, L.
Bonnetain, Franck
Mitry, E.
Bedenne, L.

June 2007

International audienceBackground: In patients (pts) with locally advanced non metastatic pancreatic ...

A Multi-Institutional Phase II Trial of Preoperative Full-Dose Gemcitabine and Concurrent Radiation for Patients With Potentially Resectable Pancreatic Carcinoma

Abstract

Extracted data

A Multi-Institutional Phase II Trial of Preoperative Full-Dose Gemcitabine and Concurrent Radiation for Patients With Potentially Resectable Pancreatic Carcinoma

Abstract

Extracted data

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