Rewarding and aversive brain stimulation opposite effects on medial thalamic units

Most of the neurons recorded from rat medial thalamus are inhibited by medial forebrain bundle and excited by reticular stimuli delivered at frequencies of 20-60 Hz. These opposite neural responses in single units parallel the opposite behavioral and motivational properties of the brain stimuli and may play a role in integrating reward and pain mechanisms.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/33959/1/0000229.pd