An N-3 ethylthiol-modified uridine has been synthesized and incorporated through solid-phase phosphoramidite chemistry at the 5'- and 3'-termini of an RNA hairpin to provide increased conformational stability via a disulfide cross-link.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/31710/1/0000646.pd
Les ARNs sont impliqués dans de nombreux processus biologiques et peuvent adopter des structures sec...
grantor: University of TorontoThe convertible nucleotide strategy allows for the concomita...
3'-Thiopurine 2'-deoxynucleosides have been incorporated into model oligodeoxynucleotides (DONs) thu...
AbstractBackground: Several factors impede the elucidation of RNA structure and function by X-ray an...
A synthetic methodology for conformationally restraining nucleic acids using disulfide cross-links i...
Protocols for postsynthetic modification of 2‐amino‐containing oligoribonucleotides with either an a...
In this review I discuss straightforward and general methods to modify nucleic acid structure with d...
International audienceAn original post-synthetic method on a solid support was developed to introduc...
Three analogs of unmodified yeast tRNAPhe, each possessing a single disulfide cross-link, have been ...
The synthesis and utilization of novel thiostatines (β-SH-substituted γ-amino acids) in the design o...
Disulfides cross-link residues in a protein that are separated in primary sequence and stabilize the...
An intramolecular DNA triple helix incorporating a disulfide cross-link has been synthesized. Potass...
Disulfides cross-link residues in a protein that are separated in primary sequence and stabilize the...
A convenient, practical route to the synthesis of disulfide-bridged oligonucleotides has been devel-...
We synthesized a new phosphoramidite building block from 18 beta-glycyrrhetinic acid. This compound ...
Les ARNs sont impliqués dans de nombreux processus biologiques et peuvent adopter des structures sec...
grantor: University of TorontoThe convertible nucleotide strategy allows for the concomita...
3'-Thiopurine 2'-deoxynucleosides have been incorporated into model oligodeoxynucleotides (DONs) thu...
AbstractBackground: Several factors impede the elucidation of RNA structure and function by X-ray an...
A synthetic methodology for conformationally restraining nucleic acids using disulfide cross-links i...
Protocols for postsynthetic modification of 2‐amino‐containing oligoribonucleotides with either an a...
In this review I discuss straightforward and general methods to modify nucleic acid structure with d...
International audienceAn original post-synthetic method on a solid support was developed to introduc...
Three analogs of unmodified yeast tRNAPhe, each possessing a single disulfide cross-link, have been ...
The synthesis and utilization of novel thiostatines (β-SH-substituted γ-amino acids) in the design o...
Disulfides cross-link residues in a protein that are separated in primary sequence and stabilize the...
An intramolecular DNA triple helix incorporating a disulfide cross-link has been synthesized. Potass...
Disulfides cross-link residues in a protein that are separated in primary sequence and stabilize the...
A convenient, practical route to the synthesis of disulfide-bridged oligonucleotides has been devel-...
We synthesized a new phosphoramidite building block from 18 beta-glycyrrhetinic acid. This compound ...
Les ARNs sont impliqués dans de nombreux processus biologiques et peuvent adopter des structures sec...
grantor: University of TorontoThe convertible nucleotide strategy allows for the concomita...
3'-Thiopurine 2'-deoxynucleosides have been incorporated into model oligodeoxynucleotides (DONs) thu...
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