DL-3,3-Difluoroglutamic acid was synthesized from a masked 3-hydroxyprolinol, 6-hydroxy-1-aza-3-oxabicyclo[3.3.0]octan-2-one, in eight steps. The described synthetic route expands the utility of fluoroproline derivatives as precursors of fluoroglutamic acids.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/30676/1/0000320.pd
Reformatsky reaction of ethyl bromodifluoroacetate with N,N-(dibenzyl)-1H-benzotriazolyl-1-methylami...
Includes bibliographical references (pages 49-55)Two fluorogenic phosphatidylcholines (PC-1 and PC-2...
Celem pracy było opracowanie drogi syntezy fluorowanych alkaloidów pirolizydynowych, któremogą być p...
Synthetic strategies toward 4-substituted 3,3-difluoropiperidines were evaluated. 4-Alkoxymethyl- an...
A number of new fluorophenyl 4-oxocyclopentane[d]isoxazolines and their dioxolane derivatives has be...
Folylpoly-gamma-glutamate synthetase (FPGS) and gamma-glutamyl hydrolase (GH) catalyze the formation...
The development of optically active fluorinated synthetic building blocks of general utility is a cu...
Synthetic routes toward new 5-amino- and 5-hydroxy-3,3-difluoropiperidines, which are of high intere...
Synthetic strategies toward 3-fluoroazetidine-3-carboxylic acid, a new cyclic fluorinated beta-amino...
Difluoropiperidines attract considerable interest from organic and medicinal chemists, but their syn...
International audienceTrifluoromethyl group containing oxazolidines (Fox) are conveniently synthesiz...
The synthesis of fluorinated analogs of glutamic acid and the synthesis of folates and antifolates c...
This paper reports exclusive γ-conjugation of poly(ethylene glycol) (PEG) to folic acid (FA) and th...
o-Aldehydocarboxylic Acids. Part I. A New General Method of Synthesising Phthalonic Acids. A Synthes...
4-Fluoroprolines are among the most useful nonnatural amino acids in chemical biology. Here, practic...
Reformatsky reaction of ethyl bromodifluoroacetate with N,N-(dibenzyl)-1H-benzotriazolyl-1-methylami...
Includes bibliographical references (pages 49-55)Two fluorogenic phosphatidylcholines (PC-1 and PC-2...
Celem pracy było opracowanie drogi syntezy fluorowanych alkaloidów pirolizydynowych, któremogą być p...
Synthetic strategies toward 4-substituted 3,3-difluoropiperidines were evaluated. 4-Alkoxymethyl- an...
A number of new fluorophenyl 4-oxocyclopentane[d]isoxazolines and their dioxolane derivatives has be...
Folylpoly-gamma-glutamate synthetase (FPGS) and gamma-glutamyl hydrolase (GH) catalyze the formation...
The development of optically active fluorinated synthetic building blocks of general utility is a cu...
Synthetic routes toward new 5-amino- and 5-hydroxy-3,3-difluoropiperidines, which are of high intere...
Synthetic strategies toward 3-fluoroazetidine-3-carboxylic acid, a new cyclic fluorinated beta-amino...
Difluoropiperidines attract considerable interest from organic and medicinal chemists, but their syn...
International audienceTrifluoromethyl group containing oxazolidines (Fox) are conveniently synthesiz...
The synthesis of fluorinated analogs of glutamic acid and the synthesis of folates and antifolates c...
This paper reports exclusive γ-conjugation of poly(ethylene glycol) (PEG) to folic acid (FA) and th...
o-Aldehydocarboxylic Acids. Part I. A New General Method of Synthesising Phthalonic Acids. A Synthes...
4-Fluoroprolines are among the most useful nonnatural amino acids in chemical biology. Here, practic...
Reformatsky reaction of ethyl bromodifluoroacetate with N,N-(dibenzyl)-1H-benzotriazolyl-1-methylami...
Includes bibliographical references (pages 49-55)Two fluorogenic phosphatidylcholines (PC-1 and PC-2...
Celem pracy było opracowanie drogi syntezy fluorowanych alkaloidów pirolizydynowych, któremogą być p...
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