Functional and structural neuropathy was examined in hyperglycemic (diabetic) BB rats maintained on small maintenance doses of insulin, hyperglycemic BB rats receiving no insulin, and BB rats in whom hypoglycemia was induced by the administration of excessive insulin doses. The data were compared with those of non-diabetic age- and sex-matched BB rats. Functional deficits and structural abnormalities were comparable in diabetic rats with and without insulin supplementation, suggesting that the generally necessary insulin dosing in this model does not per se account for the neuropathy. Hypoglycemic neuropathy was characterized by slowing of nerve conduction velocity, marked loss of anterior horn motoneurons and Wallerian degeneration, as wel...
Mitochondrial dysfunction has been proposed as a mediator of neurodegeneration in diabetes complicat...
Decreased nerve blood flow may be a pathogenetic factor in diabetic neuropathy. Previously it was sh...
Objectives. Epidemiological studies in patients with type 1 and type 2 diabetes show that hyperglyce...
Hyperglycaemia caused by insulin deficiency is believed to play a major role in the de-velopment of ...
Peripheral neuropathy is a leading complication of diabetes mellitus. Although its exact pathogenesi...
Altered sorbitol and myo-inositol metabolism, (Na,K)-ATPase function, electrochemical sodium gradien...
SUMMARY Structure and function of peripheral nerve in early insulin deficient streptozotocin diabeti...
In the experimental rat model of diabetes a slowing of nerve conduction velocity and a resistance to...
Introduction. Current clinical guidelines for management of diabetic peripheral neuropathy (DPN) emp...
Treatment-induced neuropathy in diabetes (TIND) is defined by the occurrence of an acute neuropathy ...
ABSTRACT. Rodent models of diabetes develop a slowing of nerve conduction velocity and mild axonal a...
Treatment-induced neuropathy in diabetes (TIND) is defined by the occurrence of an acute neuropathy ...
The streptozotocin (STZ)-diabetic rat, the most commonly employed model of experimental diabetic neu...
Recently a new rat model for type 2 diabetes the Zucker diabetic Sprague-Dawley (ZDSD/Pco) was creat...
The problem of diabetic neuropathy has not been studied experimentally to the same extent as have ot...
Mitochondrial dysfunction has been proposed as a mediator of neurodegeneration in diabetes complicat...
Decreased nerve blood flow may be a pathogenetic factor in diabetic neuropathy. Previously it was sh...
Objectives. Epidemiological studies in patients with type 1 and type 2 diabetes show that hyperglyce...
Hyperglycaemia caused by insulin deficiency is believed to play a major role in the de-velopment of ...
Peripheral neuropathy is a leading complication of diabetes mellitus. Although its exact pathogenesi...
Altered sorbitol and myo-inositol metabolism, (Na,K)-ATPase function, electrochemical sodium gradien...
SUMMARY Structure and function of peripheral nerve in early insulin deficient streptozotocin diabeti...
In the experimental rat model of diabetes a slowing of nerve conduction velocity and a resistance to...
Introduction. Current clinical guidelines for management of diabetic peripheral neuropathy (DPN) emp...
Treatment-induced neuropathy in diabetes (TIND) is defined by the occurrence of an acute neuropathy ...
ABSTRACT. Rodent models of diabetes develop a slowing of nerve conduction velocity and mild axonal a...
Treatment-induced neuropathy in diabetes (TIND) is defined by the occurrence of an acute neuropathy ...
The streptozotocin (STZ)-diabetic rat, the most commonly employed model of experimental diabetic neu...
Recently a new rat model for type 2 diabetes the Zucker diabetic Sprague-Dawley (ZDSD/Pco) was creat...
The problem of diabetic neuropathy has not been studied experimentally to the same extent as have ot...
Mitochondrial dysfunction has been proposed as a mediator of neurodegeneration in diabetes complicat...
Decreased nerve blood flow may be a pathogenetic factor in diabetic neuropathy. Previously it was sh...
Objectives. Epidemiological studies in patients with type 1 and type 2 diabetes show that hyperglyce...