A no-carrier added synthesis of [11C]thymidine from cyclotron produced [11C]methyl iodide is presented. The bis-silylated derivative of the lithium salt of 5-bromo-2'-deoxyuridine is treated with [11C]methyl iodide in THF at -50[deg]C giving 20-30 mCi [11C]thymidine in a 40-70% radiochemical yield. Purification is performed by reversed phase chromatography on a C18 column. The whole procedure takes 25 min and the specific activity is about 20-30 mCi/[mu]mol at the end of the synthesis.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/28118/1/0000567.pd
Achieving a 99mTc labeled thymidine radiotracer for single photon emission tomography (SPECT) is con...
The genetic probe labeled with positron emitter for monitor-ing tumor cells transfacted by herpes si...
A method of 11C-methionine synthesis using ‘bubbling’ method is presented. 11C-methionine was synthe...
A three-step synthesis of [2-11C]thymidine, using [11C]urea as precursor, is described. [2-11C]Thymi...
Compounds labelled with 11C (β+, t1/2 = 20.4 min) are used in positron emission tomography (PET), wh...
Purpose: In order to obtain a thymidine analog that might prove simpler to use for imaging DNA synth...
Combined the home made PET-MV-2-IT module with carbon-11 methyl iodide module, it was used for synth...
We describe the synthesis of 11C-labeled a-aminoisobutyric acid 2 from iodo[11C]methane and methyl N...
BACKGROUND AND METHODS: 5-Iodo-2'-deoxyuridine (IdUrd) radiolabelled with the positron emitter I or ...
[[abstract]]©2006 Elsevier - Tumor cells transduced with herpes simplex virus thymidine kinase gene ...
Tumor cells transduced with herpes simplex virus thymidine kinase gene have been intensively ap-plie...
N-Methyl carbamoylimidazole is a safe and practical alternative to methyl isocyanate for carbamoylat...
The cross-coupling of aryl bromides with [11C]CH3Li for the labelling of a variety of tracers for po...
Next-generation taxoids, such as SB-T-1214, are highly potent cytotoxic agents that exhibit remarkab...
This article describes a new method of [11C]choline synthesis for intravenous injection. We aimed at...
Achieving a 99mTc labeled thymidine radiotracer for single photon emission tomography (SPECT) is con...
The genetic probe labeled with positron emitter for monitor-ing tumor cells transfacted by herpes si...
A method of 11C-methionine synthesis using ‘bubbling’ method is presented. 11C-methionine was synthe...
A three-step synthesis of [2-11C]thymidine, using [11C]urea as precursor, is described. [2-11C]Thymi...
Compounds labelled with 11C (β+, t1/2 = 20.4 min) are used in positron emission tomography (PET), wh...
Purpose: In order to obtain a thymidine analog that might prove simpler to use for imaging DNA synth...
Combined the home made PET-MV-2-IT module with carbon-11 methyl iodide module, it was used for synth...
We describe the synthesis of 11C-labeled a-aminoisobutyric acid 2 from iodo[11C]methane and methyl N...
BACKGROUND AND METHODS: 5-Iodo-2'-deoxyuridine (IdUrd) radiolabelled with the positron emitter I or ...
[[abstract]]©2006 Elsevier - Tumor cells transduced with herpes simplex virus thymidine kinase gene ...
Tumor cells transduced with herpes simplex virus thymidine kinase gene have been intensively ap-plie...
N-Methyl carbamoylimidazole is a safe and practical alternative to methyl isocyanate for carbamoylat...
The cross-coupling of aryl bromides with [11C]CH3Li for the labelling of a variety of tracers for po...
Next-generation taxoids, such as SB-T-1214, are highly potent cytotoxic agents that exhibit remarkab...
This article describes a new method of [11C]choline synthesis for intravenous injection. We aimed at...
Achieving a 99mTc labeled thymidine radiotracer for single photon emission tomography (SPECT) is con...
The genetic probe labeled with positron emitter for monitor-ing tumor cells transfacted by herpes si...
A method of 11C-methionine synthesis using ‘bubbling’ method is presented. 11C-methionine was synthe...