Increased physical activity improves aerobic fitness but not functional walking capacity in, severely obese subjects participating in a lifestyle intervention

OBJECTIVE: To determine the relationship between change in physical activity level and change in directly measured maximal aerobic fitness in severely obese subjects participating in a 1-year lifestyle intervention, and to determine whether change in 6-min walk test (6MWT) could be used as an indicator of change in aerobic fitness. METHODS: Complete data on aerobic fitness (maximal oxygen consumption (VO2max) and time to exhaustion on the VO2max test), 6MWT, and physical activity (Actigraph GT1M accelerometer) were obtained for 21 subjects (mean age 42.6 years (standard deviation (SD) 11.0 years); mean body mass index 39.6 (SD 4.5) kg/m2). Multiple linear regression (controlling for change in body mass index) was used to analyse the relationships for: (i) changes in physical activity vs aerobic fitness and change in 6MWT; and (ii) changes in aerobic fitness vs 6MWT. RESULTS: Change in physical activity level was related to VO2max and time to exhaustion (partial r > 0.63, p 0.351) or between changes in physical activity level and 6MWT (partial r = 0.15, p = 0.531). CONCLUSION: Increased physical activity level over 1 year resulted in increased aerobic fitness in severely obese subjects. Although the sample size was small, these results suggest that change in 6MWT might not be a good indicator of maximal change in aerobic fitness in this population