Adult male Sprague-Dawley rats were subjected to acute (95 dB white noise) or chronic stress, or their combination. In comparison with unstressed controls, stressed rats were more active upon several measures of open field activity. A history of chronic stress eliminated the acute stress induced activation. Concurrent treatment of chronically stressed rats with amitriptyline or scopolamine, or with a combination of both drugs resulted in selective behavioral improvement (i.e., in motor activity, latency, defecation) for amitriptyline and combined treatment rats, with significant restoration of the normal behavioral response. Scopolamine however was only marginally effective. A higher dose of scopolamine proved effective, but only with a mar...
The present study investigated the effect of long-term D1 dopamine receptor stimulation on an animal...
Three behavioral paradigms are presented for the study of the mechanism of action of antidepressant ...
The present study investigated the effect of long-term D1 dopamine receptor stimulation on an animal...
We have previously shown that rats given stress before open field testing have elevated activity in ...
Adversity during early life can lead to diverging endocrine and behavioral responses to stress in ad...
We have proposed that chronic stress may produce motivational, behavioral, and neuroendocrine sympto...
The initial activity of a rat placed in novel surroundings (i.e., open field activity) has been take...
The aim of this work was to determine the effect of amitriptyline (AMI) on peripheral outcomes such ...
Artículo de publicación ISIBackground: Clinically depressed individuals respond to different types o...
Amphetamine and tranylcypromine are structurally related chemical isomers with pharmacologically dis...
Post-traumatic stress disorder (PTSD) displays high co-morbidity with major depression and treatment...
The early-life environment has many long-term effects on mammals. Maternal interaction and early str...
Background: The impacts of unpredictable stressors have influence on neurochemical and behavioral pa...
Background: The impacts of unpredictable stressors have influence on neurochemical and behavioral pa...
Chronic stress induces in rats a decreased reactivity toward noxious stimuli (escape deficit), which...
The present study investigated the effect of long-term D1 dopamine receptor stimulation on an animal...
Three behavioral paradigms are presented for the study of the mechanism of action of antidepressant ...
The present study investigated the effect of long-term D1 dopamine receptor stimulation on an animal...
We have previously shown that rats given stress before open field testing have elevated activity in ...
Adversity during early life can lead to diverging endocrine and behavioral responses to stress in ad...
We have proposed that chronic stress may produce motivational, behavioral, and neuroendocrine sympto...
The initial activity of a rat placed in novel surroundings (i.e., open field activity) has been take...
The aim of this work was to determine the effect of amitriptyline (AMI) on peripheral outcomes such ...
Artículo de publicación ISIBackground: Clinically depressed individuals respond to different types o...
Amphetamine and tranylcypromine are structurally related chemical isomers with pharmacologically dis...
Post-traumatic stress disorder (PTSD) displays high co-morbidity with major depression and treatment...
The early-life environment has many long-term effects on mammals. Maternal interaction and early str...
Background: The impacts of unpredictable stressors have influence on neurochemical and behavioral pa...
Background: The impacts of unpredictable stressors have influence on neurochemical and behavioral pa...
Chronic stress induces in rats a decreased reactivity toward noxious stimuli (escape deficit), which...
The present study investigated the effect of long-term D1 dopamine receptor stimulation on an animal...
Three behavioral paradigms are presented for the study of the mechanism of action of antidepressant ...
The present study investigated the effect of long-term D1 dopamine receptor stimulation on an animal...