Factors affecting anserine and carnosine levels in skeletal muscles of various animals

1. 1. Analytical procedures for anserine, carnosine and related histidine compounds in skeletal muscles are given.2. 2. The anserine/carnosine ratio in the skeletal muscles of the rat increases with age, cortisone injection and lowered food intake, and in the guinea pig muscle with strenuous exercise.3. 3. The total anserine plus carnosine in leg muscles of the cat remain constant during long periods of deep anesthesia.4. 4. Skeletal muscles of man contain carnosine but no anserine. Higher levels of carnosine and low levels of anserine are found in muscles of monkey (Rhesus).5. 5. Carnosine but no anserine is present in leg muscles of frog.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/21912/1/0000319.pd