Higher incidence of premenopausal breast cancer in less developed countries; myth or truth?
- Ghiasvand, Reza
- Adami, Hans-Olov
- Harirchi, Iraj
- Akrami, Rahim
- Zendehdel, Kazem
DOIAbstract
Background Fundamental etiologic differences have been suggested to cause earlier onset of breast cancer in less developed countries (LDCs) than in more developed countries (MDCs). We explored this hypothesis using world-wide breast cancer incidence data. Methods We compared international age-standardized incidence rates (ASR) of pre- (<50 years) and postmenopausal (≥50 years) breast cancers as well as temporal trends in ASRs of pre-and postmenopausal breast cancer among selected countries during 1975–2008. We used joinpoint log-linear regression analysis to estimate annual percent changes (APC) for premenopausal and postmenopausal breast cancer in the northern Eu...
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