Down-regulation of survivin affected by beta-catenin/TCF4 pathway plays an important role in apoptosis induced by NSAIDs indomethacin in HCT116 cells. The beta-catenin/TCF4-survivin pathway may be a potential target in treatment of colon cancer
AbstractThe prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs) has been shown to exert a...
ObjectiveSurvivin, an important inhibitor of apoptosis, is overexpressed in esophageal cancer and ne...
Cancer stem cells (CSCs) play a pivotal role in cancer relapse or metastasis. We investigated the CS...
Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) has attracted considerable attention...
(NSAIDs) involves cyclooxygenase (COX)-dependent and COX-independent mechanisms. Evidence suggests t...
Epidemiological studies have demonstrated that nonsteroidal anti-inflammatory drugs (NSAIDs) decreas...
Background: To determine in vitro if indomethacin inhibits proliferation and induces apoptosis in hu...
AIM: To study the effect of indomethacin (IN) on human colon cancer cell line SW480 with p53 mutant ...
Non-steroidal anti-inflammatory drugs (NSAIDs) have cancer preventive and tumor regressive effects i...
Colorectal cancer has provided an important model to test the stem cell hypothesis of cancer origin,...
We have evaluated the role of mitogen-activated protein kinases (MAPKs) and their relationship with ...
The prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs) has been shown to exert a chemopr...
Numerous epidemiological, in vivo and in vitro studies have demonstrated the chemopreventive potenti...
This work describes an investigation into potential mechanisms by which both the non-steroidal anti-...
In the evolution of colon rectal cancer (CRC) the imbalance between cell proliferation and apoptosis...
AbstractThe prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs) has been shown to exert a...
ObjectiveSurvivin, an important inhibitor of apoptosis, is overexpressed in esophageal cancer and ne...
Cancer stem cells (CSCs) play a pivotal role in cancer relapse or metastasis. We investigated the CS...
Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) has attracted considerable attention...
(NSAIDs) involves cyclooxygenase (COX)-dependent and COX-independent mechanisms. Evidence suggests t...
Epidemiological studies have demonstrated that nonsteroidal anti-inflammatory drugs (NSAIDs) decreas...
Background: To determine in vitro if indomethacin inhibits proliferation and induces apoptosis in hu...
AIM: To study the effect of indomethacin (IN) on human colon cancer cell line SW480 with p53 mutant ...
Non-steroidal anti-inflammatory drugs (NSAIDs) have cancer preventive and tumor regressive effects i...
Colorectal cancer has provided an important model to test the stem cell hypothesis of cancer origin,...
We have evaluated the role of mitogen-activated protein kinases (MAPKs) and their relationship with ...
The prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs) has been shown to exert a chemopr...
Numerous epidemiological, in vivo and in vitro studies have demonstrated the chemopreventive potenti...
This work describes an investigation into potential mechanisms by which both the non-steroidal anti-...
In the evolution of colon rectal cancer (CRC) the imbalance between cell proliferation and apoptosis...
AbstractThe prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs) has been shown to exert a...
ObjectiveSurvivin, an important inhibitor of apoptosis, is overexpressed in esophageal cancer and ne...
Cancer stem cells (CSCs) play a pivotal role in cancer relapse or metastasis. We investigated the CS...
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