OBJECTIVE: To quantify genetic overlap between migraine and ischemic stroke (IS) with respect to common genetic variation.METHODS: We applied 4 different approaches to large-scale meta-analyses of genome-wide data on migraine (23,285 cases and 95,425 controls) and IS (12,389 cases and 62,004 controls). First, we queried known genome-wide significant loci for both disorders, looking for potential overlap of signals. We then analyzed the overall shared genetic load using polygenic scores and estimated the genetic correlation between disease subtypes using data derived from these models. We further interrogated genomic regions of shared risk using analysis of covariance patterns between the 2 phenotypes using cross-phenotype spatial mapping.RE...
Introduction - It is unclear whether patients diagnosed according to International Classification of...
Migraine is a debilitating neurological disorder affecting around one in seven people worldwide, but...
INTRODUCTION: H.Z. and E.E. contributed equally to this work. A.M.J.M.v.d.M. and D.R.N. jointly dire...
Objective: To quantify genetic overlap between migraine and ischemic stroke (IS) with respect to com...
Objective: To quantify genetic overlap between migraine and ischemic stroke (IS) with respect to com...
OBJECTIVE: To quantify genetic overlap between migraine and ischemic stroke (IS) with respect to com...
© 2015 American Academy of Neurology. Objective: To quantify genetic overlap between migraine and is...
Objective: To apply genetic analysis of genome-wide association data to study the extent and nature ...
OBJECTIVE: To apply genetic analysis of genome-wide association data to study the extent and nature ...
Migraine is a recurrent pain condition traditionally viewed as a neurovascular disorder, but little ...
Migraine is a recurrent pain condition traditionally viewed as a neurovascular disorder, but little ...
Migraine is a recurrent pain condition traditionally viewed as a neurovascular disorder, but little ...
Migraine is a recurrent pain condition traditionally viewed as a neurovascular disorder, but little ...
Objective: to examine potential genetic relationships between migraine and the two distinct phenotyp...
Objective: To examine potential genetic relationships between migraine and the two distinct phenotyp...
Introduction - It is unclear whether patients diagnosed according to International Classification of...
Migraine is a debilitating neurological disorder affecting around one in seven people worldwide, but...
INTRODUCTION: H.Z. and E.E. contributed equally to this work. A.M.J.M.v.d.M. and D.R.N. jointly dire...
Objective: To quantify genetic overlap between migraine and ischemic stroke (IS) with respect to com...
Objective: To quantify genetic overlap between migraine and ischemic stroke (IS) with respect to com...
OBJECTIVE: To quantify genetic overlap between migraine and ischemic stroke (IS) with respect to com...
© 2015 American Academy of Neurology. Objective: To quantify genetic overlap between migraine and is...
Objective: To apply genetic analysis of genome-wide association data to study the extent and nature ...
OBJECTIVE: To apply genetic analysis of genome-wide association data to study the extent and nature ...
Migraine is a recurrent pain condition traditionally viewed as a neurovascular disorder, but little ...
Migraine is a recurrent pain condition traditionally viewed as a neurovascular disorder, but little ...
Migraine is a recurrent pain condition traditionally viewed as a neurovascular disorder, but little ...
Migraine is a recurrent pain condition traditionally viewed as a neurovascular disorder, but little ...
Objective: to examine potential genetic relationships between migraine and the two distinct phenotyp...
Objective: To examine potential genetic relationships between migraine and the two distinct phenotyp...
Introduction - It is unclear whether patients diagnosed according to International Classification of...
Migraine is a debilitating neurological disorder affecting around one in seven people worldwide, but...
INTRODUCTION: H.Z. and E.E. contributed equally to this work. A.M.J.M.v.d.M. and D.R.N. jointly dire...