Topics
epigeneticBook
hematological malignanciesDisease
Cancer cells contain multiple genetic and epigenetic changes. The relative specificity of many epigenetic changes for neoplastic cells has allowed the identification of diagnostic, prognostic and predictive biomarkers for a number of solid tumors and hematological malignancies. Moreover, epigenetically-acting drugs are already in routine use for cancer and numerous additional agents are in clinical trials. Here, we review recent progress in the development and application of epigenetic strategies for the diagnosis, risk stratification and treatment of cancer
Epigenetics connects the divide between genotype and phenotype without completely altering the genom...
The critical role of dysregulated epigenetic pathways in cancer genesis, development, and therapy ha...
Copyright © 2013 E. Hatzimichael and T. Crook.This is an open access article distributed under theCr...
Cancer cells contain multiple genetic and epigenetic changes. The relative specificity of many epige...
Cancer cells contain multiple genetic and epigenetic changes. The relative specificity of many epige...
Cancer is considered by both genetic and epigenetic pathways. Although, genetic pathways are straigh...
Cancer is initiated through both genetic and epigenetic alterations. The end-effect of such changes ...
Epigenetics' is defined as the inheritable changes in gene expression with no alterations in DN...
Epigenetic, along with genetic mechanisms, is essential for natural evolution and maintenance of spe...
Fabricio F CostaCancer Biology and Epigenomics Program, Children’s Memorial Research Cente...
Cancer is caused by aberrant genetic and epigenetic changes in genes expression. DNA methylation, hi...
Epigenetics is emerging as an important field in cancer epidemiology that promises to provide insigh...
Defects in chromatin modifiers and remodelers have been described both for hematological and solid m...
A key feature of cancer is dysregulation of gene activity and gene expression, which is driven by a ...
""Epigenetic inactivation of pivotal genes involved in correct cell growth is a hallmark of human pa...
Epigenetics connects the divide between genotype and phenotype without completely altering the genom...
The critical role of dysregulated epigenetic pathways in cancer genesis, development, and therapy ha...
Copyright © 2013 E. Hatzimichael and T. Crook.This is an open access article distributed under theCr...
Cancer cells contain multiple genetic and epigenetic changes. The relative specificity of many epige...
Cancer cells contain multiple genetic and epigenetic changes. The relative specificity of many epige...
Cancer is considered by both genetic and epigenetic pathways. Although, genetic pathways are straigh...
Cancer is initiated through both genetic and epigenetic alterations. The end-effect of such changes ...
Epigenetics' is defined as the inheritable changes in gene expression with no alterations in DN...
Epigenetic, along with genetic mechanisms, is essential for natural evolution and maintenance of spe...
Fabricio F CostaCancer Biology and Epigenomics Program, Children’s Memorial Research Cente...
Cancer is caused by aberrant genetic and epigenetic changes in genes expression. DNA methylation, hi...
Epigenetics is emerging as an important field in cancer epidemiology that promises to provide insigh...
Defects in chromatin modifiers and remodelers have been described both for hematological and solid m...
A key feature of cancer is dysregulation of gene activity and gene expression, which is driven by a ...
""Epigenetic inactivation of pivotal genes involved in correct cell growth is a hallmark of human pa...
Epigenetics connects the divide between genotype and phenotype without completely altering the genom...
The critical role of dysregulated epigenetic pathways in cancer genesis, development, and therapy ha...
Copyright © 2013 E. Hatzimichael and T. Crook.This is an open access article distributed under theCr...
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