Adverse surgical outcomes in screen-detected ductal carcinoma in situ of the breast
- Thomas, Jeremy
- Hanby, Andrew
- Pinder, Sarah E.
- Ball, Graham
- Lawrence, Gill
- Maxwell, Anthony
- Wallis, Mathew
- Evans, Andrew
- Dobson, Hilary
- Clements, Karen
- Thompson, Alastair
Publication date
July 2014
DOIAbstract
Background: The Sloane Project is the largest prospective audit of ductal carcinoma in situ (DCIS) worldwide, with over 12,000 patients registered between 2003 and 2012, accounting for 50% of screen-detected DCIS diagnosed in the United Kingdom (UK) over the period of accrual. Methods: Complete multidisciplinary data from 8313 patients with screen-detected DCIS were analysed for surgical outcome in relation to key radiological and pathological parameters for the cohort and also by hospital of treatment. Adverse surgical outcomes were defined as either failed breast conservation surgery (BCS) or mastectomy for small lesions
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