Neutrophils are known to dominate the pulmonary inflammatory process observed in cystic fibrosis (CF). An enduring paradox is how these large numbers of neutrophils fail to eradicate colonizing bacteria. Major advances in our understanding of neutrophil dysfunction in CF and its effect on the innate immune system are leading to advances in our understanding of the pathophysiology and leading directly to new therapies
Cystic fibrosis (CF) is a genetic syndrome caused by mutations in the CF Transmembrane Conductance R...
Cystic fibrosis (CF) affects 70,000 patients worldwide. Morbidity and mortality in CF is largely cau...
International audienceThe underlying cause of morbidity in cystic fibrosis (CF) is the decline in lu...
Neutrophils are known to dominate the pulmonary inflammatory process observed in cystic fibrosis (CF...
Lung injury in cystic fibrosis is caused by recurrent airway infection and inflammation. Neutrophils...
The thesis investigates reasons for a failure of neutrophils to clear pulmonary bacterial infection ...
Despite tremendous recent advances in our understanding of the molecular and cellular basis of cysti...
AbstractThe pathological hallmark of cystic fibrosis (CF) chronic inflammatory response is the massi...
Genetic defects in cystic fibrosis (CF) transmembrane conductance regulator (CFTR) gene cause CF. In...
Cystic fibrosis (CF) lung disease is characterized by an exaggerated, and extended inflammation, wit...
Summary. Although airway obstruction and chronic endobronchial infection have long been recognized a...
The interplay between airway inflammation and infection is now recognized as a major factor in the p...
Cystic fibrosis (CF), the most common lethal single-gene disorder affecting Northern Europeans and N...
Despite remarkable progress following the identification of the causing gene, the final outcome of c...
Abstract Background Cystic Fibrosis (CF) is a devastating genetic disease characterised primarily by...
Cystic fibrosis (CF) is a genetic syndrome caused by mutations in the CF Transmembrane Conductance R...
Cystic fibrosis (CF) affects 70,000 patients worldwide. Morbidity and mortality in CF is largely cau...
International audienceThe underlying cause of morbidity in cystic fibrosis (CF) is the decline in lu...
Neutrophils are known to dominate the pulmonary inflammatory process observed in cystic fibrosis (CF...
Lung injury in cystic fibrosis is caused by recurrent airway infection and inflammation. Neutrophils...
The thesis investigates reasons for a failure of neutrophils to clear pulmonary bacterial infection ...
Despite tremendous recent advances in our understanding of the molecular and cellular basis of cysti...
AbstractThe pathological hallmark of cystic fibrosis (CF) chronic inflammatory response is the massi...
Genetic defects in cystic fibrosis (CF) transmembrane conductance regulator (CFTR) gene cause CF. In...
Cystic fibrosis (CF) lung disease is characterized by an exaggerated, and extended inflammation, wit...
Summary. Although airway obstruction and chronic endobronchial infection have long been recognized a...
The interplay between airway inflammation and infection is now recognized as a major factor in the p...
Cystic fibrosis (CF), the most common lethal single-gene disorder affecting Northern Europeans and N...
Despite remarkable progress following the identification of the causing gene, the final outcome of c...
Abstract Background Cystic Fibrosis (CF) is a devastating genetic disease characterised primarily by...
Cystic fibrosis (CF) is a genetic syndrome caused by mutations in the CF Transmembrane Conductance R...
Cystic fibrosis (CF) affects 70,000 patients worldwide. Morbidity and mortality in CF is largely cau...
International audienceThe underlying cause of morbidity in cystic fibrosis (CF) is the decline in lu...
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