Tandem Michael addition and intramolecular aldol cyclization of 1,2-dideoxy-1-nitroheptitols derived from sugars
- Berrocal, M.V.
- Gil, M.V.
- Román, E.
- Serrano, J.A.
- Hursthouse, M.B.
- Light, M.E.
Publication date
May 2005
DOI Publisher
Elsevier BV ISSN
0040-4039 Citation count (estimate)
7Abstract
The base-catalyzed Michael addition of primary nitro compounds derived from sugars with 2 equiv of methyl vinyl ketone or acrolein was followed, in situ, by an asymmetric intramolecular aldol cyclization, thus yielding 2-acyl-4-glyco-4-nitrocyclohexanol derivatives with high diastereoselectivity
Add to ORKG
