Microglia are macrophage cells found throughout the brain and spinal cord, and they function as the main form of active immune defense in the central nervous system. In a normal, healthy brain, resting state microglia have a ramified morphology. After a pathological event, however, microglia transform into an activated form that has amoeboid morphology, by sensing factors that trigger cellular remodeling into the active state. Receptor-induced Ca2+ signals play a central role in microglial activation and function. Calcium signals are maintained by a process involving store-operated calcium entry (SOCE), namely the opening of plasma membrane Ca2+ channels after the release of Ca2+ from intracellular stores. Once depletion has occurred, strom...
In both excitable and non-excitable cells, calcium (Ca2+) signals are maintained by a highly integra...
Microglia, resident immune cells of the brain, react to the presence of pathogens/danger signals wit...
In vitro studies show that microglia, the resident immune cells of the brain, express neurotransmitt...
In this review we summarize mechanisms of Ca(2+) signaling in microglial cells and the impact of Ca(...
Microglia-brain macrophages are immune-competent cells of the CNS and respond to pathologic events. ...
Microglia are immune effector cells in the central nervous system that participate in tissue repair,...
STIM1 is the only currently known intracellular calcium sensor that functions as the calcium influx ...
Microglia, the innate immune sentinels of the central nervous system, are the most dynamic cells in ...
STIM1 is the only currently known intracellular calcium sensor that functions as the calcium influx ...
Glial cells exploit calcium (Ca2+) signals to perceive the information about the activity of the ner...
Calcium-mediated intercellular communication is a mechanism by which astrocytes communicate with eac...
We recently reported that lasting activation of mouse microglial cells with bacterial lipopolysaccha...
Microglia, the resident immune cells of the central nervous system, react to inflammatory stimuli in...
AbstractIn the healthy adult brain microglia, the main immune-competent cells of the CNS, have a dis...
In both excitable and non-excitable cells, calcium (Ca2+) signals are maintained by a highly integra...
In both excitable and non-excitable cells, calcium (Ca2+) signals are maintained by a highly integra...
Microglia, resident immune cells of the brain, react to the presence of pathogens/danger signals wit...
In vitro studies show that microglia, the resident immune cells of the brain, express neurotransmitt...
In this review we summarize mechanisms of Ca(2+) signaling in microglial cells and the impact of Ca(...
Microglia-brain macrophages are immune-competent cells of the CNS and respond to pathologic events. ...
Microglia are immune effector cells in the central nervous system that participate in tissue repair,...
STIM1 is the only currently known intracellular calcium sensor that functions as the calcium influx ...
Microglia, the innate immune sentinels of the central nervous system, are the most dynamic cells in ...
STIM1 is the only currently known intracellular calcium sensor that functions as the calcium influx ...
Glial cells exploit calcium (Ca2+) signals to perceive the information about the activity of the ner...
Calcium-mediated intercellular communication is a mechanism by which astrocytes communicate with eac...
We recently reported that lasting activation of mouse microglial cells with bacterial lipopolysaccha...
Microglia, the resident immune cells of the central nervous system, react to inflammatory stimuli in...
AbstractIn the healthy adult brain microglia, the main immune-competent cells of the CNS, have a dis...
In both excitable and non-excitable cells, calcium (Ca2+) signals are maintained by a highly integra...
In both excitable and non-excitable cells, calcium (Ca2+) signals are maintained by a highly integra...
Microglia, resident immune cells of the brain, react to the presence of pathogens/danger signals wit...
In vitro studies show that microglia, the resident immune cells of the brain, express neurotransmitt...