Serum N-propeptide of collagen IIA (PIIANP) as a marker of radiographic osteoarthritis burden

Large scale meta-analysis of urinary C-terminal telopeptide, serum cartilage oligomeric protein and matrix metalloprotease degraded type II collagen and their role in prevalence, incidence and progression of osteoarthritis

Valdes, AM
Hart, D
Spector, TD
Meulenbelt, I
Slagboom, EP
Chassaing, E
Arden, NK
Bierma-Zeinstra, S
Hofman, A
Uitterlinden, AG
Karsdal, M
Bay-Jensen, AC
Kloppenburg, M
Van Meurs, JB
Kroon, HM

May 2014

Objective: To evaluate the role of three cartilage-derived biomarkers on osteoarthritis (OA): urinar...

Large scale meta-analysis of urinary C-terminal telopeptide, serum cartilage oligomeric protein and matrix metalloprotease degraded type II collagen and their role in prevalence, incidence and progression of osteoarthritis.

Valdes, A
Meulenbelt, I
Chassaing, E
Arden, N
Bierma-Zeinstra, S
Hart, D
Hofman, A
Karsdal, M
Kloppenburg, M
Kroon, H
Slagboom, E
Spector, T
Uitterlinden, A
van Meurs, J
Bay-Jensen, A

January 2014

OBJECTIVE: To evaluate the role of three cartilage-derived biomarkers on osteoarthritis (OA): urinar...

Collagen Biomarkers for Arthritis Applications

James D. Birmingham
Vladimir Vilim
Virginia B. Kraus

August 2016

The most common form of chronic arthritis is osteoarthritis (OA) with prevalence as high as 80 % aft...

Serum N-propeptide of collagen IIA (PIIANP) as a marker of radiographic osteoarthritis burden.

Hikmat N Daghestani
Joanne M Jordan
Jordan B Renner
Michael Doherty
A Gerry Wilson
Virginia B Kraus

OBJECTIVE:Cartilage homeostasis relies on a balance of catabolism and anabolism of cartilage matrix....

Discovery and development of the N-terminal procollagen type II (NPII) biomarker: a tool for measuring collagen type II synthesis

Nemirovskiy, O.V.
Sunyer, T.
Aggarwal, P.
Abrams, M.
Hellio Le Graverand, M.P.
Mathews, W.R.

December 2008

SummaryObjectiveProgression of joint damage in osteoarthritis (OA) is likely to result from an imbal...

Serum levels of type IIA procollagen amino terminal propeptide (PIIANP) are decreased in patients with knee osteoarthritis and rheumatoid arthritis.

Rousseau, J.-C.
Zhu, Y.
Miossec, P.
Vignon, E.
Sandell, L.J.
Garnero, P.
Delmas, P.D.

June 2004

AbstractObjective: The aim of this study was to develop a specific immunoassay for PIIANP and measur...

Large scale meta-analysis of urinary C-terminal telopeptide, serum cartilage oligomeric protein and matrix metalloprotease degraded type II collagen and their role in prevalence, incidence and progression of osteoarthritis

Valdes, A.M.
Meulenbelt, I.
Chassaing, E.
Arden, N.K.
Bierma-Zeinstra, S.
Hart, D.
Hofman, A.
Karsdal, M.
Kloppenburg, M.
Kroon, H.M.
Slagboom, E.P.
Spector, T.D.
Uitterlinden, A.G.
van Meurs, J.B.
Bay-Jensen, A.C.

May 2014

SummaryObjectiveTo evaluate the role of three cartilage-derived biomarkers on osteoarthritis (OA): u...

Synovial fluid concentrations of the C-propeptide of type II collagen correlate with body mass index in primary knee osteoarthritis

Kobayashi, Tatsuo
Yoshihara, Yasuo
Samura, Atsuyoshi
Yamada, Harumoto
Shinmei, Masayuki
Roos, Harald
Lohmander, Stefan

January 1997

OBJECTIVE: To explore in a cross sectional study in patients with primary knee osteoarthritis (OA) t...

A Novel High Sensitivity Type II Collagen Blood-Based Biomarker, PRO-C2, for Assessment of Cartilage Formation

Yunyun Luo
Yi He
Ditte Reker
Natasja Stæhr Gudmann
Kim Henriksen
Ole Simonsen
Christoph Ladel
Martin Michaelis
Ali Mobasheri
Morten Karsdal
Anne-Christine Bay-Jensen

November 2018

N-terminal propeptide of type II collagen (PIINP) is a biomarker reflecting cartilage formation. PII...

Increased urinary excretion of C-telopeptides of type II collagen (CTX-II) predicts cartilage loss over 21 months by MRI

Dam, E.B.
Byrjalsen, I.
Karsdal, M.A.
Qvist, P.
Christiansen, C.

March 2009

SummaryObjectiveOsteoarthritis (OA) is characterized by increased bone and cartilage metabolism lead...

The ratio of type II collagen breakdown to synthesis and its relationship with the progression of knee osteoarthritis

Cahue, S.
Sharma, L.
Dunlop, D.
Ionescu, M.
Song, J.
Lobanok, T.
King, L.
Poole, A. Robin

July 2007

SummaryObjectiveTo examine whether the baseline ratio of a type II collagen breakdown marker to a sy...

PIIANP and HELIXII diurnal variation

Quintana, D.J.
Garnero, P.
Huebner, J.L.
Charni-Ben Tabassi, N.
Kraus, V.B.

October 2008

SummaryObjectiveSerum levels of procollagen type IIA N-terminal propeptide (sPIIANP) and type-II col...

Review: Collagen markers in early arthritic diseases

Elsaid, K. A.
Chichester, C. O.

March 2006

In arthritic diseases e.g. osteoarthritis (OA) and rheumatoid arthritis (RA), the stability of the c...

Anabolic and catabolic function of chondrocyte ex vivo is reflected by the metabolic processing of type II collagen

Olsen, A.K.
Sondergaard, B.C.
Byrjalsen, I.
Tanko, L.B.
Christiansen, C.
Müller, A.
Hein, G.E.
Karsdal, M.A.
Qvist, P.

March 2007

SummaryObjectiveThe aim of the present study was to investigate collagen metabolism after anabolic a...

A Highly Sensitive Biomarker of Type II Collagen C-Terminal Pro-Peptide Associated with Cartilage Formation

Helena Port
Anne-Christine Bay-Jensen
Yi He
Morten A. Karsdal
Thorbjørn Gantzel
Christian S. Thudium
Signe Holm Nielsen

December 2022

The type II collagen C-terminal pro-peptide is one of the most abundant polypeptides in cartilage. T...

Large scale meta-analysis of urinary C-terminal telopeptide, serum cartilage oligomeric protein and matrix metalloprotease degraded type II collagen and their role in prevalence, incidence and progression of osteoarthritis

Valdes, AM
Hart, D
Spector, TD
Meulenbelt, I
Slagboom, EP
Chassaing, E
Arden, NK
Bierma-Zeinstra, S
Hofman, A
Uitterlinden, AG
Karsdal, M
Bay-Jensen, AC
Kloppenburg, M
Van Meurs, JB
Kroon, HM

May 2014

Objective: To evaluate the role of three cartilage-derived biomarkers on osteoarthritis (OA): urinar...

Large scale meta-analysis of urinary C-terminal telopeptide, serum cartilage oligomeric protein and matrix metalloprotease degraded type II collagen and their role in prevalence, incidence and progression of osteoarthritis.

Valdes, A
Meulenbelt, I
Chassaing, E
Arden, N
Bierma-Zeinstra, S
Hart, D
Hofman, A
Karsdal, M
Kloppenburg, M
Kroon, H
Slagboom, E
Spector, T
Uitterlinden, A
van Meurs, J
Bay-Jensen, A

January 2014

OBJECTIVE: To evaluate the role of three cartilage-derived biomarkers on osteoarthritis (OA): urinar...

Collagen Biomarkers for Arthritis Applications

James D. Birmingham
Vladimir Vilim
Virginia B. Kraus

August 2016

The most common form of chronic arthritis is osteoarthritis (OA) with prevalence as high as 80 % aft...

Serum N-propeptide of collagen IIA (PIIANP) as a marker of radiographic osteoarthritis burden.

Hikmat N Daghestani
Joanne M Jordan
Jordan B Renner
Michael Doherty
A Gerry Wilson
Virginia B Kraus

OBJECTIVE:Cartilage homeostasis relies on a balance of catabolism and anabolism of cartilage matrix....

Discovery and development of the N-terminal procollagen type II (NPII) biomarker: a tool for measuring collagen type II synthesis

Nemirovskiy, O.V.
Sunyer, T.
Aggarwal, P.
Abrams, M.
Hellio Le Graverand, M.P.
Mathews, W.R.

December 2008

SummaryObjectiveProgression of joint damage in osteoarthritis (OA) is likely to result from an imbal...

Serum levels of type IIA procollagen amino terminal propeptide (PIIANP) are decreased in patients with knee osteoarthritis and rheumatoid arthritis.

Rousseau, J.-C.
Zhu, Y.
Miossec, P.
Vignon, E.
Sandell, L.J.
Garnero, P.
Delmas, P.D.

June 2004

AbstractObjective: The aim of this study was to develop a specific immunoassay for PIIANP and measur...

Large scale meta-analysis of urinary C-terminal telopeptide, serum cartilage oligomeric protein and matrix metalloprotease degraded type II collagen and their role in prevalence, incidence and progression of osteoarthritis

Valdes, A.M.
Meulenbelt, I.
Chassaing, E.
Arden, N.K.
Bierma-Zeinstra, S.
Hart, D.
Hofman, A.
Karsdal, M.
Kloppenburg, M.
Kroon, H.M.
Slagboom, E.P.
Spector, T.D.
Uitterlinden, A.G.
van Meurs, J.B.
Bay-Jensen, A.C.

May 2014

SummaryObjectiveTo evaluate the role of three cartilage-derived biomarkers on osteoarthritis (OA): u...

Synovial fluid concentrations of the C-propeptide of type II collagen correlate with body mass index in primary knee osteoarthritis

Kobayashi, Tatsuo
Yoshihara, Yasuo
Samura, Atsuyoshi
Yamada, Harumoto
Shinmei, Masayuki
Roos, Harald
Lohmander, Stefan

January 1997

OBJECTIVE: To explore in a cross sectional study in patients with primary knee osteoarthritis (OA) t...

A Novel High Sensitivity Type II Collagen Blood-Based Biomarker, PRO-C2, for Assessment of Cartilage Formation

Yunyun Luo
Yi He
Ditte Reker
Natasja Stæhr Gudmann
Kim Henriksen
Ole Simonsen
Christoph Ladel
Martin Michaelis
Ali Mobasheri
Morten Karsdal
Anne-Christine Bay-Jensen

November 2018

N-terminal propeptide of type II collagen (PIINP) is a biomarker reflecting cartilage formation. PII...

Increased urinary excretion of C-telopeptides of type II collagen (CTX-II) predicts cartilage loss over 21 months by MRI

Dam, E.B.
Byrjalsen, I.
Karsdal, M.A.
Qvist, P.
Christiansen, C.

March 2009

SummaryObjectiveOsteoarthritis (OA) is characterized by increased bone and cartilage metabolism lead...

The ratio of type II collagen breakdown to synthesis and its relationship with the progression of knee osteoarthritis

Cahue, S.
Sharma, L.
Dunlop, D.
Ionescu, M.
Song, J.
Lobanok, T.
King, L.
Poole, A. Robin

July 2007

SummaryObjectiveTo examine whether the baseline ratio of a type II collagen breakdown marker to a sy...

PIIANP and HELIXII diurnal variation

Quintana, D.J.
Garnero, P.
Huebner, J.L.
Charni-Ben Tabassi, N.
Kraus, V.B.

October 2008

SummaryObjectiveSerum levels of procollagen type IIA N-terminal propeptide (sPIIANP) and type-II col...

Review: Collagen markers in early arthritic diseases

Elsaid, K. A.
Chichester, C. O.

March 2006

In arthritic diseases e.g. osteoarthritis (OA) and rheumatoid arthritis (RA), the stability of the c...

Anabolic and catabolic function of chondrocyte ex vivo is reflected by the metabolic processing of type II collagen

Olsen, A.K.
Sondergaard, B.C.
Byrjalsen, I.
Tanko, L.B.
Christiansen, C.
Müller, A.
Hein, G.E.
Karsdal, M.A.
Qvist, P.

March 2007

SummaryObjectiveThe aim of the present study was to investigate collagen metabolism after anabolic a...

A Highly Sensitive Biomarker of Type II Collagen C-Terminal Pro-Peptide Associated with Cartilage Formation

Helena Port
Anne-Christine Bay-Jensen
Yi He
Morten A. Karsdal
Thorbjørn Gantzel
Christian S. Thudium
Signe Holm Nielsen

December 2022

The type II collagen C-terminal pro-peptide is one of the most abundant polypeptides in cartilage. T...

Large scale meta-analysis of urinary C-terminal telopeptide, serum cartilage oligomeric protein and matrix metalloprotease degraded type II collagen and their role in prevalence, incidence and progression of osteoarthritis

Valdes, AM
Hart, D
Spector, TD
Meulenbelt, I
Slagboom, EP
Chassaing, E
Arden, NK
Bierma-Zeinstra, S
Hofman, A
Uitterlinden, AG
Karsdal, M
Bay-Jensen, AC
Kloppenburg, M
Van Meurs, JB
Kroon, HM

May 2014

Objective: To evaluate the role of three cartilage-derived biomarkers on osteoarthritis (OA): urinar...

Large scale meta-analysis of urinary C-terminal telopeptide, serum cartilage oligomeric protein and matrix metalloprotease degraded type II collagen and their role in prevalence, incidence and progression of osteoarthritis.

Valdes, A
Meulenbelt, I
Chassaing, E
Arden, N
Bierma-Zeinstra, S
Hart, D
Hofman, A
Karsdal, M
Kloppenburg, M
Kroon, H
Slagboom, E
Spector, T
Uitterlinden, A
van Meurs, J
Bay-Jensen, A

January 2014

OBJECTIVE: To evaluate the role of three cartilage-derived biomarkers on osteoarthritis (OA): urinar...

Collagen Biomarkers for Arthritis Applications

James D. Birmingham
Vladimir Vilim
Virginia B. Kraus

August 2016

The most common form of chronic arthritis is osteoarthritis (OA) with prevalence as high as 80 % aft...

Serum N-propeptide of collagen IIA (PIIANP) as a marker of radiographic osteoarthritis burden

Abstract

Extracted data

Serum N-propeptide of collagen IIA (PIIANP) as a marker of radiographic osteoarthritis burden

Abstract

Extracted data

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