A genome-wide study of lipid response to fenofibrate in Caucasians: a combined analysis of the GOLDN and ACCORD studies

Detecting responses to treatment with fenofibrate in pedigrees

Svetlana Cherlin
Maggie Haitian Wang
Heike Bickeböller
Rita M. Cantor

September 2018

Abstract Background Fenofibrate (Fb) is a known treatment for elevated triglyceride (TG) levels. The...

A Genome-Wide Association Study For Blood Lipid Phenotypes in the Framingham Heart Study

Kathiresan, Sekar
Manning, Alisa K.
Demissie, Serkalem
D'Agostino, Ralph B.
Surti, Aarti
Guiducci, Candace
Gianniny, Lauren
Burtt, Noel P.
Melander, Olle
Orho-Melander, Marju
Arnett, Donna K.
Peloso, Gina M.
Ordovas, Jose M.
Cupples, L. Adrienne

September 2007

BACKGROUND: Blood lipid levels including low-density lipoprotein cholesterol (LDL-C), high-density l...

Replication Study of Plasma Lipoprotein Levels-Associated Polymorphisms Identified in Recent Genome-Wide Association Studies

Bryant, Emily Kate

June 2011

Cardiovascular disease (CVD) is a major public health concern in the U.S., and is the leading cause ...

A genome-wide study of lipid response to fenofibrate in Caucasians: a combined analysis of the GOLDN and ACCORD studies

Irvin, Marguerite R.
Rotroff, Daniel M.
Aslibekyan, Stella
Zhi, Degui
Hidalgo, Bertha
Motsinger-Reif, Alison
Marvel, Skylar
Srinivasasainagendra, Vinodh
Claas, Steven A.
Buse, John B.
Straka, Robert J.
Ordovas, Jose M.
Borecki, Ingrid B.
Guo, Xiuqing
Chen, Ida Y.D.
Rotter, Jerome I.
Wagner, Michael J.
Arnett, Donna K.

January 2016

Fibrates are commonly prescribed for hypertriglyceridemia but also lower low-density lipoprotein cho...

Variants Identified in a GWAS Meta-Analysis for Blood Lipids Are Associated with the Lipid Response to Fenofibrate

Stella Aslibekyan (123439)
Mark O. Goodarzi (123440)
Alexis C. Frazier-Wood (123443)
Xiaofei Yan (123447)
Marguerite R. Irvin (102149)
Eric Kim (105536)
Hemant K. Tiwari (123452)
Xiuqing Guo (73591)
Robert J. Straka (123457)
Kent D. Taylor (123459)
Michael Y. Tsai (113677)
Paul N. Hopkins (123462)
Stanley G. Korenman (123463)
Ingrid B. Borecki (113678)
Yii-Der I. Chen (123464)
Jose M. Ordovas (2605621)
Jerome I. Rotter (103729)
Donna K. Arnett (123469)

October 2012

<div><p>A recent large-scale meta-analysis of genome-wide studies has identified 95 loci, 59 of them...

An Exome-Wide Sequencing Study of Lipid Response to High-Fat Meal and Fenofibrate in Caucasians from the GOLDN Cohort

Geng, Xin
Irvin, Marguerite R.
Hidalgo, Bertha
Aslibekyan, Stella
Srinivasasainagendra, Vinodh
An, Ping
Frazier-Wood, Alexis C.
Tiwari, Hemant K.
Dave, Tushar
Ryan, Kathleen
Ordovas, Jose M.
Straka, Robert J.
Feitosa, Mary F.
Hopkins, Paul N.
Borecki, Ingrid
Province, Michael A.
Mitchell, Braxton D.
Arnett, Donna K.
Zhi, Degui

February 2018

Our understanding of genetic influences on the response of lipids to specific interventions is limit...

An Investigation of the Effects of Lipid-Lowering Medications: Genome-Wide Linkage Analysis of Lipids in the HyperGEN Study

Wu, Jun
Province, Michael A.
Coon, Hilary
Hunt, Steven C.
Eckfeldt, John H.
Arnett, Donna K.
Heiss, Gerardo
Lewis, Cora E.
Ellison, R. Curtis
Rao, Dabeeru C
Rice, Treva
Kraja, Aldi T.

September 2007

BACKGROUND: Use of anti-hyperlipidemic medications compromises genetic analysis because of altered l...

An investigation of the effects of lipid-lowering medications: genome-wide linkage analysis of lipids in the HyperGEN study

Wu, Jun
Province, Michael A
Coon, Hilary
Hunt, Steven C
Eckfeldt, John H
Arnett, Donna K
Heiss, Gerardo
Lewis, Cora E
Ellison, R Curtis
Rao, Dabeeru C
Rice, Treva
Kraja, Aldi T

September 2007

Abstract Background Use of anti-hyperlipidemic medications compromises genetic analysis because of a...

Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease

Waterworth, D. M.
Ricketts, S. L.
Song, K.
Chen, L.
Zhao, J. H.
Ripatti, S.
Aulchenko, Y. S.
Zhang, W.
Yuan, X.
Lim, N.
Luan, J.
Ashford, S.
Wheeler, E.
Young, E. H.
Hadley, D.
Thompson, J. R.
Braund, P. S.
Johnson, T.
Struchalin, M.
Surakka, I.
Luben, R.
Khaw, K.-T.
Rodwell, S. A.
Loos, R. J. F.
Boekholdt, S. M.
Inouye, M.
Deloukas, P.
Elliott, P.
Schlessinger, D.
Sanna, S.
Scuteri, A.
Jackson, A.

January 2010

Genetic studies might provide new insights into the biological mechanisms underlying lipid metabolis...

Finding genes and variants for lipid levels after genome-wide association analysis

Willer, Cristen J.
Mohlke, Karen L.

January 2012

We review the main findings from genome-wide association studies (GWAS) for levels of HDL-cholestero...

Biological, clinical and population relevance of 95 loci for blood lipids

Teslovich, Tanya M.
Musunuru, Kiran
Smith, Albert V.
Edmondson, Andrew C.
Stylianou, Ioannis M.
Koseki, Masahiro
Pirruccello, James P.
Ripatti, Samuli
Chasman, Daniel I.
Willer, Cristen J.
Johansen, Christopher T.
Fouchier, Sigrid W.
Isaacs, Aaron
Peloso, Gina M.
Barbalic, Maja
Ricketts, Sally L.
Bis, Joshua C.
Aulchenko, Yurii S.
Thorleifsson, Gudmar
Feitosa, Mary F.
Chambers, John
Orho-Melander, Marju
Melander, Olle
Johnson, Toby
Li, Xiaohui
Guo, Xiuqing
Li, Mingyao
Shin Cho, Yoon
Jin Go, Min
Jin Kim, Young
Lee, Jong-Young
Park, Taesung

January 2010

Serum concentrations of total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density...

Genetic Determinants of Lipid Traits in Diverse Populations from the Population Architecture using Genomics and Epidemiology (PAGE) Study

Dumitrescu, Logan
Carty, Cara L.
Taylor, Kira
Schumacher, Fredrick R.
Hindorff, Lucia A.
Ambite, José L.
Anderson, Garnet
Best, Lyle G.
Brown-Gentry, Kristin
Bůžková, Petra
Carlson, Christopher S.
Cochran, Barbara
Cole, Shelley A.
Devereux, Richard B.
Duggan, Dave
Eaton, Charles B.
Fornage, Myriam
Franceschini, Nora
Haessler, Jeff
Howard, Barbara V.
Johnson, Karen C.
Laston, Sandra
Kolonel, Laurence N.
Lee, Elisa T.
MacCluer, Jean W.
Manolio, Teri A.
Pendergrass, Sarah A.
Quibrera, Miguel
Shohet, Ralph V.
Wilkens, Lynne R.
Haiman, Christopher A.
Le Marchand, Loïc

January 2011

For the past five years, genome-wide association studies (GWAS) have identified hundreds of common v...

Family-based genome-wide association of inflammation biomarkers and fenofibrate treatment response in the GOLDN study

Sarmistha Das
Pronoy Kanti Mondal
Saurabh Ghosh
Indranil Mukhopadhyay

September 2018

Abstract In this paper we analyzed whole-genome genetic information provided by GAW20 from the Genet...

Genomics of post-prandial lipidomic phenotypes in the Genetics of Lipid lowering Drugs and Diet Network (GOLDN) study

Irvin, Marguerite R
Zhi, Degui
Aslibekyan, Stella
Claas, Steven A
Absher, Devin M
Ordovas, Jose M
Tiwari, Hemant K
Watkins, Steve
Arnett, Donna K

January 2014

BACKGROUND: Increased postprandial lipid (PPL) response to dietary fat intake is a heritable risk fa...

Detecting responses to treatment with fenofibrate in pedigrees.

Cherlin, Svetlana
Wang, Maggie Haitian
Bickeböller, Heike
Cantor, Rita M

September 2018

BackgroundFenofibrate (Fb) is a known treatment for elevated triglyceride (TG) levels. The Genetics ...

Detecting responses to treatment with fenofibrate in pedigrees

Svetlana Cherlin
Maggie Haitian Wang
Heike Bickeböller
Rita M. Cantor

September 2018

Abstract Background Fenofibrate (Fb) is a known treatment for elevated triglyceride (TG) levels. The...

A Genome-Wide Association Study For Blood Lipid Phenotypes in the Framingham Heart Study

Kathiresan, Sekar
Manning, Alisa K.
Demissie, Serkalem
D'Agostino, Ralph B.
Surti, Aarti
Guiducci, Candace
Gianniny, Lauren
Burtt, Noel P.
Melander, Olle
Orho-Melander, Marju
Arnett, Donna K.
Peloso, Gina M.
Ordovas, Jose M.
Cupples, L. Adrienne

September 2007

BACKGROUND: Blood lipid levels including low-density lipoprotein cholesterol (LDL-C), high-density l...

Replication Study of Plasma Lipoprotein Levels-Associated Polymorphisms Identified in Recent Genome-Wide Association Studies

Bryant, Emily Kate

June 2011

Cardiovascular disease (CVD) is a major public health concern in the U.S., and is the leading cause ...

A genome-wide study of lipid response to fenofibrate in Caucasians: a combined analysis of the GOLDN and ACCORD studies

Irvin, Marguerite R.
Rotroff, Daniel M.
Aslibekyan, Stella
Zhi, Degui
Hidalgo, Bertha
Motsinger-Reif, Alison
Marvel, Skylar
Srinivasasainagendra, Vinodh
Claas, Steven A.
Buse, John B.
Straka, Robert J.
Ordovas, Jose M.
Borecki, Ingrid B.
Guo, Xiuqing
Chen, Ida Y.D.
Rotter, Jerome I.
Wagner, Michael J.
Arnett, Donna K.

January 2016

Fibrates are commonly prescribed for hypertriglyceridemia but also lower low-density lipoprotein cho...

Variants Identified in a GWAS Meta-Analysis for Blood Lipids Are Associated with the Lipid Response to Fenofibrate

Stella Aslibekyan (123439)
Mark O. Goodarzi (123440)
Alexis C. Frazier-Wood (123443)
Xiaofei Yan (123447)
Marguerite R. Irvin (102149)
Eric Kim (105536)
Hemant K. Tiwari (123452)
Xiuqing Guo (73591)
Robert J. Straka (123457)
Kent D. Taylor (123459)
Michael Y. Tsai (113677)
Paul N. Hopkins (123462)
Stanley G. Korenman (123463)
Ingrid B. Borecki (113678)
Yii-Der I. Chen (123464)
Jose M. Ordovas (2605621)
Jerome I. Rotter (103729)
Donna K. Arnett (123469)

October 2012

<div><p>A recent large-scale meta-analysis of genome-wide studies has identified 95 loci, 59 of them...

An Exome-Wide Sequencing Study of Lipid Response to High-Fat Meal and Fenofibrate in Caucasians from the GOLDN Cohort

Geng, Xin
Irvin, Marguerite R.
Hidalgo, Bertha
Aslibekyan, Stella
Srinivasasainagendra, Vinodh
An, Ping
Frazier-Wood, Alexis C.
Tiwari, Hemant K.
Dave, Tushar
Ryan, Kathleen
Ordovas, Jose M.
Straka, Robert J.
Feitosa, Mary F.
Hopkins, Paul N.
Borecki, Ingrid
Province, Michael A.
Mitchell, Braxton D.
Arnett, Donna K.
Zhi, Degui

February 2018

Our understanding of genetic influences on the response of lipids to specific interventions is limit...

An Investigation of the Effects of Lipid-Lowering Medications: Genome-Wide Linkage Analysis of Lipids in the HyperGEN Study

Wu, Jun
Province, Michael A.
Coon, Hilary
Hunt, Steven C.
Eckfeldt, John H.
Arnett, Donna K.
Heiss, Gerardo
Lewis, Cora E.
Ellison, R. Curtis
Rao, Dabeeru C
Rice, Treva
Kraja, Aldi T.

September 2007

BACKGROUND: Use of anti-hyperlipidemic medications compromises genetic analysis because of altered l...

An investigation of the effects of lipid-lowering medications: genome-wide linkage analysis of lipids in the HyperGEN study

Wu, Jun
Province, Michael A
Coon, Hilary
Hunt, Steven C
Eckfeldt, John H
Arnett, Donna K
Heiss, Gerardo
Lewis, Cora E
Ellison, R Curtis
Rao, Dabeeru C
Rice, Treva
Kraja, Aldi T

September 2007

Abstract Background Use of anti-hyperlipidemic medications compromises genetic analysis because of a...

Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease

Waterworth, D. M.
Ricketts, S. L.
Song, K.
Chen, L.
Zhao, J. H.
Ripatti, S.
Aulchenko, Y. S.
Zhang, W.
Yuan, X.
Lim, N.
Luan, J.
Ashford, S.
Wheeler, E.
Young, E. H.
Hadley, D.
Thompson, J. R.
Braund, P. S.
Johnson, T.
Struchalin, M.
Surakka, I.
Luben, R.
Khaw, K.-T.
Rodwell, S. A.
Loos, R. J. F.
Boekholdt, S. M.
Inouye, M.
Deloukas, P.
Elliott, P.
Schlessinger, D.
Sanna, S.
Scuteri, A.
Jackson, A.

January 2010

Genetic studies might provide new insights into the biological mechanisms underlying lipid metabolis...

Finding genes and variants for lipid levels after genome-wide association analysis

Willer, Cristen J.
Mohlke, Karen L.

January 2012

We review the main findings from genome-wide association studies (GWAS) for levels of HDL-cholestero...

Biological, clinical and population relevance of 95 loci for blood lipids

Teslovich, Tanya M.
Musunuru, Kiran
Smith, Albert V.
Edmondson, Andrew C.
Stylianou, Ioannis M.
Koseki, Masahiro
Pirruccello, James P.
Ripatti, Samuli
Chasman, Daniel I.
Willer, Cristen J.
Johansen, Christopher T.
Fouchier, Sigrid W.
Isaacs, Aaron
Peloso, Gina M.
Barbalic, Maja
Ricketts, Sally L.
Bis, Joshua C.
Aulchenko, Yurii S.
Thorleifsson, Gudmar
Feitosa, Mary F.
Chambers, John
Orho-Melander, Marju
Melander, Olle
Johnson, Toby
Li, Xiaohui
Guo, Xiuqing
Li, Mingyao
Shin Cho, Yoon
Jin Go, Min
Jin Kim, Young
Lee, Jong-Young
Park, Taesung

January 2010

Serum concentrations of total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density...

Genetic Determinants of Lipid Traits in Diverse Populations from the Population Architecture using Genomics and Epidemiology (PAGE) Study

Dumitrescu, Logan
Carty, Cara L.
Taylor, Kira
Schumacher, Fredrick R.
Hindorff, Lucia A.
Ambite, José L.
Anderson, Garnet
Best, Lyle G.
Brown-Gentry, Kristin
Bůžková, Petra
Carlson, Christopher S.
Cochran, Barbara
Cole, Shelley A.
Devereux, Richard B.
Duggan, Dave
Eaton, Charles B.
Fornage, Myriam
Franceschini, Nora
Haessler, Jeff
Howard, Barbara V.
Johnson, Karen C.
Laston, Sandra
Kolonel, Laurence N.
Lee, Elisa T.
MacCluer, Jean W.
Manolio, Teri A.
Pendergrass, Sarah A.
Quibrera, Miguel
Shohet, Ralph V.
Wilkens, Lynne R.
Haiman, Christopher A.
Le Marchand, Loïc

January 2011

For the past five years, genome-wide association studies (GWAS) have identified hundreds of common v...

Family-based genome-wide association of inflammation biomarkers and fenofibrate treatment response in the GOLDN study

Sarmistha Das
Pronoy Kanti Mondal
Saurabh Ghosh
Indranil Mukhopadhyay

September 2018

Abstract In this paper we analyzed whole-genome genetic information provided by GAW20 from the Genet...

Genomics of post-prandial lipidomic phenotypes in the Genetics of Lipid lowering Drugs and Diet Network (GOLDN) study

Irvin, Marguerite R
Zhi, Degui
Aslibekyan, Stella
Claas, Steven A
Absher, Devin M
Ordovas, Jose M
Tiwari, Hemant K
Watkins, Steve
Arnett, Donna K

January 2014

BACKGROUND: Increased postprandial lipid (PPL) response to dietary fat intake is a heritable risk fa...

Detecting responses to treatment with fenofibrate in pedigrees.

Cherlin, Svetlana
Wang, Maggie Haitian
Bickeböller, Heike
Cantor, Rita M

September 2018

BackgroundFenofibrate (Fb) is a known treatment for elevated triglyceride (TG) levels. The Genetics ...

Detecting responses to treatment with fenofibrate in pedigrees

Svetlana Cherlin
Maggie Haitian Wang
Heike Bickeböller
Rita M. Cantor

September 2018

Abstract Background Fenofibrate (Fb) is a known treatment for elevated triglyceride (TG) levels. The...

A Genome-Wide Association Study For Blood Lipid Phenotypes in the Framingham Heart Study

Kathiresan, Sekar
Manning, Alisa K.
Demissie, Serkalem
D'Agostino, Ralph B.
Surti, Aarti
Guiducci, Candace
Gianniny, Lauren
Burtt, Noel P.
Melander, Olle
Orho-Melander, Marju
Arnett, Donna K.
Peloso, Gina M.
Ordovas, Jose M.
Cupples, L. Adrienne

September 2007

BACKGROUND: Blood lipid levels including low-density lipoprotein cholesterol (LDL-C), high-density l...

Replication Study of Plasma Lipoprotein Levels-Associated Polymorphisms Identified in Recent Genome-Wide Association Studies

Bryant, Emily Kate

June 2011

Cardiovascular disease (CVD) is a major public health concern in the U.S., and is the leading cause ...

A genome-wide study of lipid response to fenofibrate in Caucasians: a combined analysis of the GOLDN and ACCORD studies

Abstract

Extracted data

A genome-wide study of lipid response to fenofibrate in Caucasians: a combined analysis of the GOLDN and ACCORD studies

Abstract

Extracted data

Topics

Related items

Topics

Related items