Human birth presents an abrupt transition from intrauterine to extrauterine life. Here we introduce a novel Maturation Index (MI) that considers the relative importance of gestational age at birth and postnatal age at scan in a General Linear Model. The MI is then applied to Diffusion Tensor Imaging (DTI) in newborns for characterizing typical white matter development in neonates. DTI was performed cross-sectionally in 47 neonates (gestational age at birth=39.1±1.6 weeks [GA], postnatal age at scan=25.5±12.2days [SA]). Radial diffusivity (RD), axial diffusivity (AD) and fractional anisotropy (FA) along 27 white matter fiber tracts were considered. The MI was used to characterize inflection in maturation at the time of birth using GLM estima...
While the majority of axonal organization is established by birth in mammalian brains, axonal wiring...
The neonatal brain undergoes rapid development after birth, including the growth and maturation of t...
Rapid and important cerebral developmental changes occur between the third trimester of gestation an...
Human birth presents an abrupt transition from intrauterine to extrauterine life. Here we introduce ...
PURPOSE: Diffusion magnetic resonance imaging (dMRI) studies report altered white matter (WM) develo...
AbstractBrain white matter connections have become a focus of major interest with important maturati...
An estimated 15 million infants are born preterm every year and, thanks to improvements in neonatal ...
pre-printBACKGROUND AND PURPOSE: The early postnatal period is perhaps the most dynamic phase of whi...
Few large-scale studies have been done to characterize the normal human brain white matter growth in...
AbstractPreterm birth is a major public health concern, with the severity and occurrence of adverse ...
Preterm birth disrupts and alters the complex developmental processes in the cerebral cortex. This d...
White matter microstructure, essential for efficient and coordinated transmission of neural communic...
Brain white matter connections have become a focus of major interest with important maturational pro...
Diffusion-weighted imaging (DWI) provides information about tissue maturation not seen on convention...
We investigated the isotropic diffusion coefficient (D') and fractional anisotropy (FA) in white mat...
While the majority of axonal organization is established by birth in mammalian brains, axonal wiring...
The neonatal brain undergoes rapid development after birth, including the growth and maturation of t...
Rapid and important cerebral developmental changes occur between the third trimester of gestation an...
Human birth presents an abrupt transition from intrauterine to extrauterine life. Here we introduce ...
PURPOSE: Diffusion magnetic resonance imaging (dMRI) studies report altered white matter (WM) develo...
AbstractBrain white matter connections have become a focus of major interest with important maturati...
An estimated 15 million infants are born preterm every year and, thanks to improvements in neonatal ...
pre-printBACKGROUND AND PURPOSE: The early postnatal period is perhaps the most dynamic phase of whi...
Few large-scale studies have been done to characterize the normal human brain white matter growth in...
AbstractPreterm birth is a major public health concern, with the severity and occurrence of adverse ...
Preterm birth disrupts and alters the complex developmental processes in the cerebral cortex. This d...
White matter microstructure, essential for efficient and coordinated transmission of neural communic...
Brain white matter connections have become a focus of major interest with important maturational pro...
Diffusion-weighted imaging (DWI) provides information about tissue maturation not seen on convention...
We investigated the isotropic diffusion coefficient (D') and fractional anisotropy (FA) in white mat...
While the majority of axonal organization is established by birth in mammalian brains, axonal wiring...
The neonatal brain undergoes rapid development after birth, including the growth and maturation of t...
Rapid and important cerebral developmental changes occur between the third trimester of gestation an...