Nine-Year Effects of 3.7 Years of Intensive Glycemic Control on Cardiovascular Outcomes
- Gerstein, Hertzel C.
- Beavers, Daniel P.
- Bertoni, Alain G.
- Bigger, J. Thomas
- Buse, John B.
- Craven, Timothy E.
- Cushman, William C.
- Fonseca, Vivian
- Geller, Nancy L.
- Giddings, Stephen J.
- Grimm, Richard H.
- Genuth, Saul
- Hramiak, Irene
- Ismail-Beigi, Faramarz
- Jimenez, Carlos R. Lopez
- Kirby, Ruth
- Probstfield, Jeffrey
- Riddle, Matthew C.
- Seaquist, Elizabeth R.
- Friedewald, William T.
DOIAbstract
In the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial, ∼4 years of intensive versus standard glycemic control in participants with type 2 diabetes and other cardiovascular risk factors had a neutral effect on the composite cardiovascular outcome, increased cardiovascular and total mortality, and reduced nonfatal myocardial infarction. Effects of the intervention during prolonged follow-up were analyzed
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