Performance of Three-Biomarker Immunohistochemistry for Intrinsic Breast Cancer Subtyping in the AMBER Consortium
- Allott, Emma H.
- Cohen, Stephanie M.
- Geradts, Joseph
- Sun, Xuezheng
- Khoury, Thaer
- Bshara, Wiam
- Zirpoli, Gary R.
- Miller, C. Ryan
- Hwang, Helena
- Thorne, Leigh B.
- O'Connor, Siobhan
- Tse, Chiu-Kit
- Bell, Mary B.
- Hu, Zhiyuan
- Li, Yan
- Kirk, Erin L.
- Bethea, Traci N.
- Perou, Charles M.
- Palmer, Julie R.
- Ambrosone, Christine B.
- Olshan, Andrew F.
- Troester, Melissa A.
DOIAbstract
Classification of breast cancer into intrinsic subtypes has clinical and epidemiologic importance. To examine accuracy of immunohistochemistry (IHC)-based methods for identifying intrinsic subtypes, a three-biomarker IHC panel was compared to the clinical record and RNA-based intrinsic (PAM50) subtypes
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