Biomarkers and degree of atherosclerosis are independently associated with incident atherosclerotic cardiovascular disease in a primary prevention cohort: The ARIC study
- Agarwala, Anandita
- Virani, Salim
- Couper, David
- Chambless, Lloyd
- Boerwinkle, Eric
- Astor, Brad C.
- Hoogeveen, Ron C.
- Coresh, Joe
- Sharrett, A. Richey
- Folsom, Aaron R.
- Mosley, Tom
- Ballantyne, Christie M.
- Nambi, Vijay
DOIAbstract
Biomarkers and atherosclerosis imaging have been studied individually for association with incident cardiovascular disease (CVD); however, limited data exist on whether the biomarkers are associated with events with a similar magnitude in the presence of atherosclerosis. In this study, we assessed whether the presence of atherosclerosis as measured by carotid intima media thickness (cIMT) affects the association between biomarkers known to be associated with coronary heart disease (CHD) and incident cardiovascular disease (CVD) in a primary prevention cohort
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