Metabolomics of Chronic Kidney Disease Progression: A Case-Control Analysis in the Chronic Renal Insufficiency Cohort Study

Urinary metabolites associate with the rate of kidney function decline in patients with autosomal dominant polycystic kidney disease.

Shosha E I Dekker
Aswin Verhoeven
Darius Soonawala
Dorien J M Peters
Johan W de Fijter
Oleg A Mayboroda
DIPAK Consortium

January 2020

BACKGROUND:The variable course of autosomal dominant polycystic kidney disease (ADPKD), and the adve...

Differential metabolomic signatures of declining renal function in Types 1 and 2 diabetes

Manca, Maria Laura
Solini, Anna
Haukka, Jani K.
Sandholm, Niina
Forsblom, Carol
Groop, Per Henrik
Ferrannini, Ele

October 2021

NMR-based metabolomics in differential diagnosis of Chronic Kidney Disease (CKD) subtypes

Chasapi, SA
Karagkouni, E
Kalavrizioti, D
Vamvakas, S
Zompra, A
Takis, PG
Goumenos, DS
Spyroulias, GA

May 2022

Chronic Kidney Disease (CKD) is considered as a major public health problem as it can lead to end-st...

Metabolomics of Chronic Kidney Disease Progression: A Case-Control Analysis in the Chronic Renal Insufficiency Cohort Study

Rhee, Eugene P.
Clish, Clary B.
Wenger, Julia
Roy, Jason
Elmariah, Sammy
Pierce, Kerry A.
Bullock, Kevin
Anderson, Amanda H.
Gerszten, Robert E.
Feldman, Harold I.

January 2016

Whereas several longitudinal metabolomics studies have been conducted in individuals with normal eGF...

Editorial Metabolite Markers of Incident CKD Risk

Eugene P. Rhee
Harold I. Feldman
Doi /cjn

September 2016

The systematic analysis of metabolites (e.g., sugars, amino acids, organic acids, lipids, etc.) in b...

Chronic Kidney Disease Cohort Studies: A Guide to Metabolome Analyses

Schultheiss, Ulla T
Kosch, Robin
Kotsis, Fruzsina
Altenbuchinger, Michael
Zacharias, Helena

January 2021

Kidney diseases still pose one of the biggest challenges for global health, and their heterogeneity ...

Serum Metabolite Concentrations and Decreased GFR in the General Population

Goek, Oemer-Necmi
Doering, Angela
Gieger, Christian
Heier, Margit
Koenig, Wolfgang
Prehn, Cornelia
Roemisch-Margl, Werner
Wang-Sattler, Rui
Illig, Thomas
Suhre, Karsten
Sekula, Peggy
Zhai, Guangju
Adamski, Jerzy
Koettgen, Anna
Meisinger, Christa

August 2012

Background: Metabolites such as creatinine and urea are established kidney function markers. High-th...

Metabolomic Markers of Kidney Function Decline in Patients With Diabetes: Evidence From the Chronic Renal Insufficiency Cohort (CRIC) Study.

Kwan, Brian
Fuhrer, Tobias
Zhang, Jing
Darshi, Manjula
Van Espen, Benjamin
Montemayor, Daniel
de Boer, Ian H
Dobre, Mirela
Hsu, Chi-Yuan
Kelly, Tanika N
Raj, Dominic S
Rao, Panduranga S
Saraf, Santosh L
Scialla, Julia
Waikar, Sushrut S
Sharma, Kumar
Natarajan, Loki
CRIC Study Investigators

October 2020

Rationale & objectiveBiomarkers that provide reliable evidence of future diabetic kidney disease...

Increased urinary osmolyte excretion indicates chronic kidney disease severity and progression rate

Gil, Ryan B
Ortiz, Alberto
Sanchez-Niño, Maria D
Markoska, Katerina
Schepers, Eva
Vanholder, Raymond
Glorieux, Griet
Schmitt-Kopplin, Philippe
Heinzmann, Silke S

January 2018

Background: Chronic kidney disease (CKD) is a recognized global health problem. While some CKD patie...

Metabolomics biomarkers and the risk of overall mortality and ESRD in CKD: Results from the Progredir Cohort.

Silvia M Titan
Gabriela Venturini
Kallyandra Padilha
Alessandra C Goulart
Paulo A Lotufo
Isabela J Bensenor
Jose E Krieger
Ravi I Thadhani
Eugene P Rhee
Alexandre C Pereira

January 2019

INTRODUCTION:Studies on metabolomics and CKD have primarily addressed CKD incidence defined as a dec...

Assessment of metabolomic and proteomic biomarkers in detection and prognosis of progression of renal function in chronic kidney disease.

Esther Nkuipou-Kenfack
Flore Duranton
Nathalie Gayrard
Àngel Argilés
Ulrika Lundin
Klaus M Weinberger
Mohammed Dakna
Christian Delles
William Mullen
Holger Husi
Julie Klein
Thomas Koeck
Petra Zürbig
Harald Mischak

Chronic kidney disease (CKD) is part of a number of systemic and renal diseases and may reach epidem...

High-Throughput Metabolomics and Diabetic Kidney Disease Progression: Evidence from the Chronic Renal Insufficiency (CRIC) Study

Zhang, Jing
Fuhrer, Tobias
Ye, Hongping
Kwan, Brian
Montemayor, Daniel
Tumova, Jana
Darshi, Manjula
Afshinnia, Farsad
Scialla, Julia J.
Anderson, Amanda
Porter, Anna C.
Taliercio, Jonathan J.
Rincon-Choles, Hernan
Rao, Panduranga
Xie, Dawei
Feldman, Harold
Sauer, Uwe
Sharma, Kumar
Natarajan, Loki

April 2022

Introduction: Metabolomics could offer novel prognostic biomarkers and elucidate mechanisms of diabe...

Urinary metabolites associate with the rate of kidney function decline in patients with autosomal dominant polycystic kidney disease

Dekker, S.E.I.
Verhoeven, A.
Soonawala, D.
Peters, D.J.M.
Fijter, J.W. de
Mayboroda, O.A.
DIPAK Consortium

May 2020

BackgroundThe variable course of autosomal dominant polycystic kidney disease (ADPKD), and the adven...

Urine Metabolite Levels, Adverse Kidney Outcomes, and Mortality in CKD Patients: A Metabolome-wide Association Study

Steinbrenner, Inga
Schultheiss, Ulla T.
Kotsis, Fruzsina
Schlosser, Pascal
Stockmann, Helena
Mohney, Robert P.
Schmid, Matthias
Oefner, Peter J.
Eckardt, Kai-Uwe
Köttgen, Anna
Sekula, Peggy
Eckardt, Kai-Uwe
Meiselbach, Heike
Schneider, Markus P.
Schiffer, Mario
Prokosch, Hans-Ulrich
Bärthlein, Barbara
Beck, Andreas
Reis, André
Ekici, Arif B.
Becker, Susanne
Becker-Grosspitsch, Dinah
Alberth-Schmidt, Ulrike
Hausknecht, Birgit
Weigel, Anke
Walz, Gerd
Köttgen, Anna
Schultheiß, Ulla T.
Kotsis, Fruzsina
Meder, Simone
Mitsch, Erna
Reinhard, Ursula
Floege, Jürgen
Saritas, Turgay
Schaeffner, Elke
Baid-Agrawal, Seema
Theisen, Kerstin
Haller, Hermann
Menne, Jan
Zeier, Martin
Sommerer, Claudia
Theilinger, Johanna
Wolf, Gunter
Busch, Martin
Paul, Rainer
Sitter, Thomas
Wanner, Christoph
Krane, Vera
Börner-Klein, Antje
Bauer, Britta
Kronenberg, Florian
Raschenberger, Julia
Kollerits, Barbara
Forer, Lukas
Schönherr, Sebastian
Weissensteiner, Hansi
Oefner, Peter J.
Gronwald, Wolfram
Schmid, Matthias
Nadal, Jennifer

April 2021

Rationale & objective: Mechanisms underlying the variable course of disease progression in patients ...

Metabolomics biomarkers and the risk of overall mortality and ESRD in CKD: Results from the Progredir Cohort

Silvia M. Titan (6475763)
Gabriela Venturini (6475766)
Kallyandra Padilha (6475769)
Alessandra C. Goulart (739633)
Paulo A. Lotufo (65859)
Isabela J. Bensenor (6475772)
Jose E. Krieger (244163)
Ravi I. Thadhani (126784)
Eugene P. Rhee (849367)
Alexandre C. Pereira (232570)

March 2019

IntroductionStudies on metabolomics and CKD have primarily addressed CKD incidence defined as a decl...

Urinary metabolites associate with the rate of kidney function decline in patients with autosomal dominant polycystic kidney disease.

Shosha E I Dekker
Aswin Verhoeven
Darius Soonawala
Dorien J M Peters
Johan W de Fijter
Oleg A Mayboroda
DIPAK Consortium

January 2020

BACKGROUND:The variable course of autosomal dominant polycystic kidney disease (ADPKD), and the adve...

Differential metabolomic signatures of declining renal function in Types 1 and 2 diabetes

Manca, Maria Laura
Solini, Anna
Haukka, Jani K.
Sandholm, Niina
Forsblom, Carol
Groop, Per Henrik
Ferrannini, Ele

October 2021

NMR-based metabolomics in differential diagnosis of Chronic Kidney Disease (CKD) subtypes

Chasapi, SA
Karagkouni, E
Kalavrizioti, D
Vamvakas, S
Zompra, A
Takis, PG
Goumenos, DS
Spyroulias, GA

May 2022

Chronic Kidney Disease (CKD) is considered as a major public health problem as it can lead to end-st...

Metabolomics of Chronic Kidney Disease Progression: A Case-Control Analysis in the Chronic Renal Insufficiency Cohort Study

Rhee, Eugene P.
Clish, Clary B.
Wenger, Julia
Roy, Jason
Elmariah, Sammy
Pierce, Kerry A.
Bullock, Kevin
Anderson, Amanda H.
Gerszten, Robert E.
Feldman, Harold I.

January 2016

Whereas several longitudinal metabolomics studies have been conducted in individuals with normal eGF...

Editorial Metabolite Markers of Incident CKD Risk

Eugene P. Rhee
Harold I. Feldman
Doi /cjn

September 2016

The systematic analysis of metabolites (e.g., sugars, amino acids, organic acids, lipids, etc.) in b...

Chronic Kidney Disease Cohort Studies: A Guide to Metabolome Analyses

Schultheiss, Ulla T
Kosch, Robin
Kotsis, Fruzsina
Altenbuchinger, Michael
Zacharias, Helena

January 2021

Kidney diseases still pose one of the biggest challenges for global health, and their heterogeneity ...

Serum Metabolite Concentrations and Decreased GFR in the General Population

Goek, Oemer-Necmi
Doering, Angela
Gieger, Christian
Heier, Margit
Koenig, Wolfgang
Prehn, Cornelia
Roemisch-Margl, Werner
Wang-Sattler, Rui
Illig, Thomas
Suhre, Karsten
Sekula, Peggy
Zhai, Guangju
Adamski, Jerzy
Koettgen, Anna
Meisinger, Christa

August 2012

Background: Metabolites such as creatinine and urea are established kidney function markers. High-th...

Metabolomic Markers of Kidney Function Decline in Patients With Diabetes: Evidence From the Chronic Renal Insufficiency Cohort (CRIC) Study.

Kwan, Brian
Fuhrer, Tobias
Zhang, Jing
Darshi, Manjula
Van Espen, Benjamin
Montemayor, Daniel
de Boer, Ian H
Dobre, Mirela
Hsu, Chi-Yuan
Kelly, Tanika N
Raj, Dominic S
Rao, Panduranga S
Saraf, Santosh L
Scialla, Julia
Waikar, Sushrut S
Sharma, Kumar
Natarajan, Loki
CRIC Study Investigators

October 2020

Rationale & objectiveBiomarkers that provide reliable evidence of future diabetic kidney disease...

Increased urinary osmolyte excretion indicates chronic kidney disease severity and progression rate

Gil, Ryan B
Ortiz, Alberto
Sanchez-Niño, Maria D
Markoska, Katerina
Schepers, Eva
Vanholder, Raymond
Glorieux, Griet
Schmitt-Kopplin, Philippe
Heinzmann, Silke S

January 2018

Background: Chronic kidney disease (CKD) is a recognized global health problem. While some CKD patie...

Metabolomics biomarkers and the risk of overall mortality and ESRD in CKD: Results from the Progredir Cohort.

Silvia M Titan
Gabriela Venturini
Kallyandra Padilha
Alessandra C Goulart
Paulo A Lotufo
Isabela J Bensenor
Jose E Krieger
Ravi I Thadhani
Eugene P Rhee
Alexandre C Pereira

January 2019

INTRODUCTION:Studies on metabolomics and CKD have primarily addressed CKD incidence defined as a dec...

Assessment of metabolomic and proteomic biomarkers in detection and prognosis of progression of renal function in chronic kidney disease.

Esther Nkuipou-Kenfack
Flore Duranton
Nathalie Gayrard
Àngel Argilés
Ulrika Lundin
Klaus M Weinberger
Mohammed Dakna
Christian Delles
William Mullen
Holger Husi
Julie Klein
Thomas Koeck
Petra Zürbig
Harald Mischak

Chronic kidney disease (CKD) is part of a number of systemic and renal diseases and may reach epidem...

High-Throughput Metabolomics and Diabetic Kidney Disease Progression: Evidence from the Chronic Renal Insufficiency (CRIC) Study

Zhang, Jing
Fuhrer, Tobias
Ye, Hongping
Kwan, Brian
Montemayor, Daniel
Tumova, Jana
Darshi, Manjula
Afshinnia, Farsad
Scialla, Julia J.
Anderson, Amanda
Porter, Anna C.
Taliercio, Jonathan J.
Rincon-Choles, Hernan
Rao, Panduranga
Xie, Dawei
Feldman, Harold
Sauer, Uwe
Sharma, Kumar
Natarajan, Loki

April 2022

Introduction: Metabolomics could offer novel prognostic biomarkers and elucidate mechanisms of diabe...

Urinary metabolites associate with the rate of kidney function decline in patients with autosomal dominant polycystic kidney disease

Dekker, S.E.I.
Verhoeven, A.
Soonawala, D.
Peters, D.J.M.
Fijter, J.W. de
Mayboroda, O.A.
DIPAK Consortium

May 2020

BackgroundThe variable course of autosomal dominant polycystic kidney disease (ADPKD), and the adven...

Urine Metabolite Levels, Adverse Kidney Outcomes, and Mortality in CKD Patients: A Metabolome-wide Association Study

Steinbrenner, Inga
Schultheiss, Ulla T.
Kotsis, Fruzsina
Schlosser, Pascal
Stockmann, Helena
Mohney, Robert P.
Schmid, Matthias
Oefner, Peter J.
Eckardt, Kai-Uwe
Köttgen, Anna
Sekula, Peggy
Eckardt, Kai-Uwe
Meiselbach, Heike
Schneider, Markus P.
Schiffer, Mario
Prokosch, Hans-Ulrich
Bärthlein, Barbara
Beck, Andreas
Reis, André
Ekici, Arif B.
Becker, Susanne
Becker-Grosspitsch, Dinah
Alberth-Schmidt, Ulrike
Hausknecht, Birgit
Weigel, Anke
Walz, Gerd
Köttgen, Anna
Schultheiß, Ulla T.
Kotsis, Fruzsina
Meder, Simone
Mitsch, Erna
Reinhard, Ursula
Floege, Jürgen
Saritas, Turgay
Schaeffner, Elke
Baid-Agrawal, Seema
Theisen, Kerstin
Haller, Hermann
Menne, Jan
Zeier, Martin
Sommerer, Claudia
Theilinger, Johanna
Wolf, Gunter
Busch, Martin
Paul, Rainer
Sitter, Thomas
Wanner, Christoph
Krane, Vera
Börner-Klein, Antje
Bauer, Britta
Kronenberg, Florian
Raschenberger, Julia
Kollerits, Barbara
Forer, Lukas
Schönherr, Sebastian
Weissensteiner, Hansi
Oefner, Peter J.
Gronwald, Wolfram
Schmid, Matthias
Nadal, Jennifer

April 2021

Rationale & objective: Mechanisms underlying the variable course of disease progression in patients ...

Metabolomics biomarkers and the risk of overall mortality and ESRD in CKD: Results from the Progredir Cohort

Silvia M. Titan (6475763)
Gabriela Venturini (6475766)
Kallyandra Padilha (6475769)
Alessandra C. Goulart (739633)
Paulo A. Lotufo (65859)
Isabela J. Bensenor (6475772)
Jose E. Krieger (244163)
Ravi I. Thadhani (126784)
Eugene P. Rhee (849367)
Alexandre C. Pereira (232570)

March 2019

IntroductionStudies on metabolomics and CKD have primarily addressed CKD incidence defined as a decl...

Urinary metabolites associate with the rate of kidney function decline in patients with autosomal dominant polycystic kidney disease.

Shosha E I Dekker
Aswin Verhoeven
Darius Soonawala
Dorien J M Peters
Johan W de Fijter
Oleg A Mayboroda
DIPAK Consortium

January 2020

BACKGROUND:The variable course of autosomal dominant polycystic kidney disease (ADPKD), and the adve...

Differential metabolomic signatures of declining renal function in Types 1 and 2 diabetes

Manca, Maria Laura
Solini, Anna
Haukka, Jani K.
Sandholm, Niina
Forsblom, Carol
Groop, Per Henrik
Ferrannini, Ele

October 2021

NMR-based metabolomics in differential diagnosis of Chronic Kidney Disease (CKD) subtypes

Chasapi, SA
Karagkouni, E
Kalavrizioti, D
Vamvakas, S
Zompra, A
Takis, PG
Goumenos, DS
Spyroulias, GA

May 2022

Chronic Kidney Disease (CKD) is considered as a major public health problem as it can lead to end-st...

Metabolomics of Chronic Kidney Disease Progression: A Case-Control Analysis in the Chronic Renal Insufficiency Cohort Study

Abstract

Extracted data

Metabolomics of Chronic Kidney Disease Progression: A Case-Control Analysis in the Chronic Renal Insufficiency Cohort Study

Abstract

Extracted data

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