The fungal kingdom has made considerable contributions to the production of peptide secondary metabolites, many of them with therapeutic potential, e.g. the immunosuppressant cyclosporine and the antifungal echinocandins. The detailed investigation of the marine-derived fungus Stachylidium sp. was the main purpose of this research, which focused on the isolation, structural elucidation and biosynthesis of novel cyclic peptides
Filamentous fungi have long been recognized as prolific producers of natural products due in a consi...
Development of new drugs, especially in the area of oncological and infectious diseases, represents ...
The objective of this thesis was the investigation of the secondary metabolites produced by selected...
The marine environment is distinguished by unique groups of organisms being the source of a wide arr...
The marine habitat has been proven to be a rich source for both macro- and microorganisms that produ...
Microbial natural product discovery was revitalized in recent years driven by the discovery of crypt...
This thesis describes the isolation and structure elucidation of ten novel secondary metabolites fro...
Herein, we report the targeted isolation and characterization of four linear nonribosomally synthes...
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. ...
Many of the pharmaceutical agents that are used clinically were developed from natural products and ...
Plants and the fungi that colonize them (endophytic fungi) are prolific producers of the kinds of st...
Complex secondary metabolites display diverse biological activities and together with their derivati...
The marine-sponge-derived fungus <i>Stachylidium</i> sp. 293 K04 produces the <i>N</i>-methylated pe...
Secondary metabolites originated from plants, bacteria and fungi constitute a large group of compoun...
This thesis is separated in three main parts including a general introduction, three chapters based ...
Filamentous fungi have long been recognized as prolific producers of natural products due in a consi...
Development of new drugs, especially in the area of oncological and infectious diseases, represents ...
The objective of this thesis was the investigation of the secondary metabolites produced by selected...
The marine environment is distinguished by unique groups of organisms being the source of a wide arr...
The marine habitat has been proven to be a rich source for both macro- and microorganisms that produ...
Microbial natural product discovery was revitalized in recent years driven by the discovery of crypt...
This thesis describes the isolation and structure elucidation of ten novel secondary metabolites fro...
Herein, we report the targeted isolation and characterization of four linear nonribosomally synthes...
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. ...
Many of the pharmaceutical agents that are used clinically were developed from natural products and ...
Plants and the fungi that colonize them (endophytic fungi) are prolific producers of the kinds of st...
Complex secondary metabolites display diverse biological activities and together with their derivati...
The marine-sponge-derived fungus <i>Stachylidium</i> sp. 293 K04 produces the <i>N</i>-methylated pe...
Secondary metabolites originated from plants, bacteria and fungi constitute a large group of compoun...
This thesis is separated in three main parts including a general introduction, three chapters based ...
Filamentous fungi have long been recognized as prolific producers of natural products due in a consi...
Development of new drugs, especially in the area of oncological and infectious diseases, represents ...
The objective of this thesis was the investigation of the secondary metabolites produced by selected...