Railway dispatchers reschedule trains in real-time in order to limit the propagation of disturbances and to regulate traffic in their respective dispatching areas by minimizing the deviation from the off-line timetable. However, the decisions taken in one area may influence the quality and even the feasibility of train schedules in the other areas. Regional control centers coordinate the dispatchers’ work for multiple areas in order to regulate traffic at the global level and to avoid situations of global infeasibility. Differently from the dispatcher problem, the coordination activity of regional control centers is still underinvestigated, even if this activity is a key factor for effective traffic management. This paper studies the pro...