Successful wound healing in skin depends on the interplay of a multitude of different cell types, including immune cells, fibroblasts and keratinocytes, which are responding to signals from chemokines, cytokines and growth factors. Activin A is a growth and differentiation factor that is strongly induced at the wound site rapidly after injury and promotes reepithelialization and granulation tissue formation to achieve wound closure and restore tissue integrity. Our laboratory previously showed that overexpression of activin under control of the keratin 14 promoter in the basal layer of the epidermis in mice leads to accelerated wound closure, but at the same time predisposes to an enhanced fibrotic response at later stages of repair. Since ...
The growth and differentiation factor activin A is a key regulator of tissue repair, inflammation, f...
Cytokines and growth factors are known to play an important role in the skin wound closure process; ...
Objective: While tissue injury and repair are known to involve adaptive immunity, the profile of lym...
Foxp3-expressing regulatory T cells (Tregs) reside in tissues where they control inflammation and me...
Abstract As the body’s integumentary system, the skin is vulnerable to injuries. The subsequent woun...
Recently we demonstrated a strong induction of activin expression after skin injury, suggesting a fu...
Wound healing is an orchestrated process consisting of three overlapping phases: inflammation, resto...
Reepithelialization and granulation tissue formation during cutaneous wound repair are mediated by a...
AbstractActivins are members of the transforming growth factor β (TGFβ) superfamily, which comprises...
Regulatory T cells (Tregs) use multiple mechanisms to attenuate inflammation and prevent autoimmunit...
Activin is an important orchestrator of wound repair, but its potential role in skin carcinogenesis ...
Activin is an important orchestrator of wound repair, but its potential role in skin carcinogenesis ...
Activin is an important orchestrator of wound repair, but its potential role in skin carcinogenesis ...
<p>Forty four mice were randomly assigned to PBS group and Act B group (n = 22). (A) Activin B promo...
The growth and differentiation factor activin A is a key regulator of tissue repair, inflammation, f...
The growth and differentiation factor activin A is a key regulator of tissue repair, inflammation, f...
Cytokines and growth factors are known to play an important role in the skin wound closure process; ...
Objective: While tissue injury and repair are known to involve adaptive immunity, the profile of lym...
Foxp3-expressing regulatory T cells (Tregs) reside in tissues where they control inflammation and me...
Abstract As the body’s integumentary system, the skin is vulnerable to injuries. The subsequent woun...
Recently we demonstrated a strong induction of activin expression after skin injury, suggesting a fu...
Wound healing is an orchestrated process consisting of three overlapping phases: inflammation, resto...
Reepithelialization and granulation tissue formation during cutaneous wound repair are mediated by a...
AbstractActivins are members of the transforming growth factor β (TGFβ) superfamily, which comprises...
Regulatory T cells (Tregs) use multiple mechanisms to attenuate inflammation and prevent autoimmunit...
Activin is an important orchestrator of wound repair, but its potential role in skin carcinogenesis ...
Activin is an important orchestrator of wound repair, but its potential role in skin carcinogenesis ...
Activin is an important orchestrator of wound repair, but its potential role in skin carcinogenesis ...
<p>Forty four mice were randomly assigned to PBS group and Act B group (n = 22). (A) Activin B promo...
The growth and differentiation factor activin A is a key regulator of tissue repair, inflammation, f...
The growth and differentiation factor activin A is a key regulator of tissue repair, inflammation, f...
Cytokines and growth factors are known to play an important role in the skin wound closure process; ...
Objective: While tissue injury and repair are known to involve adaptive immunity, the profile of lym...