Add to ORKGAdvanced glycation end products are known to play an important role in the diabetes complications, such as diabetic nephropathy. Most known pathways of diabetic complications involve oxidative stress, that have pivotal role in cell dysfunction onset and progression of angiopathies. This review will explore how AGEs cause endothelial dysfunction in diabetes and what current biochemical mechanisms have been proposed as an explanation for the development of diabetic nephropathy.Keywords: Type 2 diabetes mellitus; advanced glycation end products; endothelial dysfunction; hyperglycemia; oxidative stress; vascular complication; diabetic nephropathy
Diabetic nephropathy is a major cause of morbidity and mortality in diabetic patients. Two key mecha...
Diabetic nephropathy (DN) is a major cause of morbidity and mortality in diabetic patients and a lea...
Diabetic patients are postulated to be in a perpetual state of oxidative stress and inflammation at ...
Advanced glycation end products are known to play an important role in the diabetes complications, s...
Advanced glycation end products are known to play an important role in the diabetes complications, s...
Advanced glycation end products are known to play an important role in the diabetes complications, s...
Advanced glycation end products are known to play an important role in the diabetes complications, s...
About 246 million people worldwide had diabetes in 2007. The global figure of people with diabetes i...
International audienceDiabetes mellitus is a multifactorial disease, classically influenced by genet...
International audienceDiabetes mellitus is a multifactorial disease, classically influenced by genet...
International audienceDiabetes mellitus is a multifactorial disease, classically influenced by genet...
Type 2 diabetes mellitus (T2DM) is a very complex and multifactorial metabolic disease characterized...
International audienceAlterations of renal endothelial cells play a crucial role in the initiation a...
International audienceAlterations of renal endothelial cells play a crucial role in the initiation a...
Hyperglycemia accelerates the formation of advanced glycation end products (AGEs). AGEs are a hetero...
Diabetic nephropathy is a major cause of morbidity and mortality in diabetic patients. Two key mecha...
Diabetic nephropathy (DN) is a major cause of morbidity and mortality in diabetic patients and a lea...
Diabetic patients are postulated to be in a perpetual state of oxidative stress and inflammation at ...
Advanced glycation end products are known to play an important role in the diabetes complications, s...
Advanced glycation end products are known to play an important role in the diabetes complications, s...
Advanced glycation end products are known to play an important role in the diabetes complications, s...
Advanced glycation end products are known to play an important role in the diabetes complications, s...
About 246 million people worldwide had diabetes in 2007. The global figure of people with diabetes i...
International audienceDiabetes mellitus is a multifactorial disease, classically influenced by genet...
International audienceDiabetes mellitus is a multifactorial disease, classically influenced by genet...
International audienceDiabetes mellitus is a multifactorial disease, classically influenced by genet...
Type 2 diabetes mellitus (T2DM) is a very complex and multifactorial metabolic disease characterized...
International audienceAlterations of renal endothelial cells play a crucial role in the initiation a...
International audienceAlterations of renal endothelial cells play a crucial role in the initiation a...
Hyperglycemia accelerates the formation of advanced glycation end products (AGEs). AGEs are a hetero...
Diabetic nephropathy is a major cause of morbidity and mortality in diabetic patients. Two key mecha...
Diabetic nephropathy (DN) is a major cause of morbidity and mortality in diabetic patients and a lea...
Diabetic patients are postulated to be in a perpetual state of oxidative stress and inflammation at ...