Benzo[a]pyrene (BaP) is one of the most potent mutagens and carcinogens known. The metabolic pathway of BaP involves several steps initiated by cytochromeP450 (CYP) enzymes such as CYP1A1 to give the ultimate carcinogen benzo(a)pyrene-7,8-diol-9,10-epoxide (BPDE). BPDE is responsible for genotoxic effects by alkylating the DNA at the N2 position of guanine bases. Rutaecarpine, a pentacyclic indolopyridoquinazolinone alkaloid isolated from the unripe fruit of Evodia rutaecarpa, has been used in traditional medicine to treat various diseases. It has been reported as a CYP1 family inducer
Rutaecarpine is an indolopyridoquinazolinone alkaloid isolated from Evodiarutaecarpa and related her...
Benzo[a]pyrene (BAP) is a commonly occurring carcinogen found in cigarette smoke and burnt meats. P...
13 Abstract An environmental pollutant and a human carcinogen benzo[a]pyrene (BaP) is after its acti...
Benzo[a]pyrene (BaP) is one of the most potent mutagens and carcinogens known. The metabolic pathway...
Benzo[a]pyrene (BaP), is one of the most potent mutagens and carcinogens known. It requires metaboli...
Benzo[a]pyrene (BaP), is one of the most potent mutagens and carcinogens known. It requires metaboli...
The overall five-year survival rate for patients with esophageal cancer is low (15 to 25%) because o...
Reactive drug metabolites have been always considered mediators of drug-induced toxicities and risk ...
It has been reported that hepatic microsomal cytochrome P450 (CYP) 2E1 is responsible for the metabo...
The dried fruits of Evodia rutaecarpa Bentham have been used widely as a herbal medicine for the tre...
The dried fruits of Evodia rutaecarpa Bentham have been used widely as a herbal medicine for the tre...
The overexpression of adenosine triphosphate (ATP)-binding cassette (ABC) subfamily B member 1 (ABCB...
The metabolism and subsequent binding of benzo(a)pyrene (BaP) to DNA represent the initial steps in ...
The metabolism and subsequent binding of benzo(a)pyrene (BaP) to DNA represent the initial steps in ...
Abstract Evodiamine and rutaecarpine are the main active indoloquinazoline alkaloids of the herbal m...
Rutaecarpine is an indolopyridoquinazolinone alkaloid isolated from Evodiarutaecarpa and related her...
Benzo[a]pyrene (BAP) is a commonly occurring carcinogen found in cigarette smoke and burnt meats. P...
13 Abstract An environmental pollutant and a human carcinogen benzo[a]pyrene (BaP) is after its acti...
Benzo[a]pyrene (BaP) is one of the most potent mutagens and carcinogens known. The metabolic pathway...
Benzo[a]pyrene (BaP), is one of the most potent mutagens and carcinogens known. It requires metaboli...
Benzo[a]pyrene (BaP), is one of the most potent mutagens and carcinogens known. It requires metaboli...
The overall five-year survival rate for patients with esophageal cancer is low (15 to 25%) because o...
Reactive drug metabolites have been always considered mediators of drug-induced toxicities and risk ...
It has been reported that hepatic microsomal cytochrome P450 (CYP) 2E1 is responsible for the metabo...
The dried fruits of Evodia rutaecarpa Bentham have been used widely as a herbal medicine for the tre...
The dried fruits of Evodia rutaecarpa Bentham have been used widely as a herbal medicine for the tre...
The overexpression of adenosine triphosphate (ATP)-binding cassette (ABC) subfamily B member 1 (ABCB...
The metabolism and subsequent binding of benzo(a)pyrene (BaP) to DNA represent the initial steps in ...
The metabolism and subsequent binding of benzo(a)pyrene (BaP) to DNA represent the initial steps in ...
Abstract Evodiamine and rutaecarpine are the main active indoloquinazoline alkaloids of the herbal m...
Rutaecarpine is an indolopyridoquinazolinone alkaloid isolated from Evodiarutaecarpa and related her...
Benzo[a]pyrene (BAP) is a commonly occurring carcinogen found in cigarette smoke and burnt meats. P...
13 Abstract An environmental pollutant and a human carcinogen benzo[a]pyrene (BaP) is after its acti...
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