GENDER DIFFERENCES IN AORTIC ENDOTHELIAL FUNCTION OF STREPTOZOTOCIN–INDUCED DIABETIC RATS: POSSIBLE INVOLVEMENT OF PROTEIN KINASE C BETA AND NITIC OXIDE PRODUCTION

Little is known of the interaction between diabetes and gender in the vasculature. The objective of this study was to investigate whether there are gender differences in rat aortic endothelial function in streptozotocin (STZ, 60mg/kg, iv)-induced diabetes and the roles of protein kinase C beta (PKCβ) and nitric oxide (NO)