The synthesis of novel multifunctional oligosaccharide tags with amino, azido, and alkyne termini is described. Tags with an amino terminus can be introduced into the carbohydrate at the reducing end through reductive amination, while 1,3-dipolar cycloaddition (“click chemistry”) can be used to label azido sugars with oligosaccharide tags having an alkyne terminus and vice versa
Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompati...
Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompati...
Sugar moieties are present in a wide range of bioactive molecules. Thus, having versatile and fast m...
The synthesis of novel multifunctional oligosaccharide tags with amino, azido, and alkyne termini is...
Oligosaccharides play very crucial biological roles in the human body. They are structurally diverse...
Carbohydrates play vital roles in numerous biological processes. Separation and structural elucidati...
Carbohydrates play central roles in many cellular processes, and structure-activity studies of carbo...
A large variety of biomolecules such as lipids, DNA, carbohydrates and proteins exist inside cells. ...
Trivalent glycoconjugates, each bearing a biotin side arm in addition to three different sugar ligan...
The oligosaccharide tag I from our lab combines UV-activity for detection and bioaffinity for purifi...
Bioorthogonal is defined as not interfering or interacting with biology. Chemical reactions that ar...
The importance of bioconjugates within the field of chemistry drives the need for novelmethodologies...
When cross-linking biomolecules to surfaces or to other biomolecules, the use of appropriate spacer ...
The azide−alkyne cycloaddition provides a powerful tool for bio-orthogonal labeling of proteins, nuc...
Many naturally occurring glycosidic compounds are of high interest in pharmaceutical, food and deter...
Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompati...
Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompati...
Sugar moieties are present in a wide range of bioactive molecules. Thus, having versatile and fast m...
The synthesis of novel multifunctional oligosaccharide tags with amino, azido, and alkyne termini is...
Oligosaccharides play very crucial biological roles in the human body. They are structurally diverse...
Carbohydrates play vital roles in numerous biological processes. Separation and structural elucidati...
Carbohydrates play central roles in many cellular processes, and structure-activity studies of carbo...
A large variety of biomolecules such as lipids, DNA, carbohydrates and proteins exist inside cells. ...
Trivalent glycoconjugates, each bearing a biotin side arm in addition to three different sugar ligan...
The oligosaccharide tag I from our lab combines UV-activity for detection and bioaffinity for purifi...
Bioorthogonal is defined as not interfering or interacting with biology. Chemical reactions that ar...
The importance of bioconjugates within the field of chemistry drives the need for novelmethodologies...
When cross-linking biomolecules to surfaces or to other biomolecules, the use of appropriate spacer ...
The azide−alkyne cycloaddition provides a powerful tool for bio-orthogonal labeling of proteins, nuc...
Many naturally occurring glycosidic compounds are of high interest in pharmaceutical, food and deter...
Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompati...
Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompati...
Sugar moieties are present in a wide range of bioactive molecules. Thus, having versatile and fast m...