Construction of CaF2-appended PVA nanofibre scaffold

In this work, a new material, calcium fluoride (CaF2)-appended poly(vinyl alcohol) (PVA) nanofibre scaffold, was prepared through electrospinning technique successfully. Scanning electron microscopy result showed that the morphology of the fibres was uniform and smooth, and the average diameter of the fibres was about 200 nm. Transmission electron microscopy results showed that many CaF2 nanoparticles were well dispersed in the PVA fibre matrix. The water-resistant ability of the scaffold was improved through intermolecular crosslinking of PVA by formaldehyde vapour. This novel material seems to be a promising scaffold for bone tissue engineering