Conventional treatments for solid tumors involve removing the malignant tissues by surgery followed by chemotherapy and/or radiotherapy. Despite the effectiveness of these therapies, the side effects of chemotherapy and radiotherapy are very high because of lack of specificity to target malignant cells. Another problem is the development of resistance to these treatments by cancer cells Targeted drug delivery strategies have been developed to improve therapeutic agents efficacy and to reduce non-specific side effects by delivering the therapeutic agents specifically to target cells. Several approaches have been investigated to achieve this aim. The differences in cell surface receptors expression have widely been used to deliver therapeutic...
Using antibody/aptamer-drug conjugates can be a promising method for decreasing toxicity, while incr...
Using antibody/aptamer-drug conjugates can be a promising method for decreasing toxicity, while incr...
Triple-negative breast cancer (TNBC) is a group of heterogeneous and refractory breast cancers with ...
Treatment of cancer, especially of solid tumors, is challenging and today classical chemotherapy is ...
Treatment of cancer, especially of solid tumors, is challenging and today classical chemotherapy is ...
One hundred years ago, Dr. Paul Ehrlich popularized the “magic bullet” concept for cancer therapy in...
Abstract In the last two decades there is substantial development in the diagnostic and therapy of m...
[[abstract]]©2009 Wiley- The conjugation of antitumor drugs to targeting reagents such as antibodies...
Antibody-drug conjugates (ADCs) combine the potency of cytotoxic drugs with the specificity of monoc...
The innovative development and success of monoclonal antibodies (mAbs) was essential in the race to ...
Innumerable people worldwide die of cancer every year, although pharmaceutical therapy has actualize...
Despite the different therapeutic options available, more than 10 million deaths every year are caus...
Abnormal structural and molecular changes in malignant tissues were thoroughly investigated and util...
AbstractMany evolving treatments for cancer patients are based on the targeted delivery of therapeut...
Abstract The combination of targeted drug delivery and controlled release technology may pave the ro...
Using antibody/aptamer-drug conjugates can be a promising method for decreasing toxicity, while incr...
Using antibody/aptamer-drug conjugates can be a promising method for decreasing toxicity, while incr...
Triple-negative breast cancer (TNBC) is a group of heterogeneous and refractory breast cancers with ...
Treatment of cancer, especially of solid tumors, is challenging and today classical chemotherapy is ...
Treatment of cancer, especially of solid tumors, is challenging and today classical chemotherapy is ...
One hundred years ago, Dr. Paul Ehrlich popularized the “magic bullet” concept for cancer therapy in...
Abstract In the last two decades there is substantial development in the diagnostic and therapy of m...
[[abstract]]©2009 Wiley- The conjugation of antitumor drugs to targeting reagents such as antibodies...
Antibody-drug conjugates (ADCs) combine the potency of cytotoxic drugs with the specificity of monoc...
The innovative development and success of monoclonal antibodies (mAbs) was essential in the race to ...
Innumerable people worldwide die of cancer every year, although pharmaceutical therapy has actualize...
Despite the different therapeutic options available, more than 10 million deaths every year are caus...
Abnormal structural and molecular changes in malignant tissues were thoroughly investigated and util...
AbstractMany evolving treatments for cancer patients are based on the targeted delivery of therapeut...
Abstract The combination of targeted drug delivery and controlled release technology may pave the ro...
Using antibody/aptamer-drug conjugates can be a promising method for decreasing toxicity, while incr...
Using antibody/aptamer-drug conjugates can be a promising method for decreasing toxicity, while incr...
Triple-negative breast cancer (TNBC) is a group of heterogeneous and refractory breast cancers with ...