Add to ORKGSynthesis of a series of new ketoprofenamides (3a-h) is described. Amide formation was achieved by aminolysis of ketoprofen benzotriazolide (2) with various amines: primary, secondary, hydroxylamine and amino acid β-alanine. The structures of synthesized compounds were characterized by means of IR, 1H and 13C NMR spectroscopies and elemental analysis. The synthesized compounds are potential prodrugs of a well-known NSAID ketoprofen
In the present study, five derivatives have been designed to be synthesized as possible mutual prodr...
There will always be a need for new pharmaceuticals as long as there are those that will be around t...
International audienceA series of substituted 6-nitrophenylpropanamide derivatives (1-20) were synth...
Synthesis of a series of new ketoprofenamides (3a-h) is described. Amide formation was achieved by a...
Synthesis of a series of new ketoprofenamides (3a-h) is described. Amide formation was achieved by a...
Synthesis of a series of new ketoprofenamides (3a-h) is described. Amide formation was achieved by a...
A series of novel ketoprofen derivatives 4a-j bearing both amide and carbamate functionalities were ...
The carboxylic acid groups of (S) ketoprofen and (S) ibuprofen were brought into reaction with subst...
A convenient synthetic method for the preparation of novel NSAID twin esters 6a-i containing amino a...
PubMedID: 8876939The synthesis of amide prodrugs of some 2-arylpropionic acids (ibuprofen, naproxen,...
A Series Of Potential Biologically Active Compounds Have Been Synthesized Through The Derivatization...
A convenient synthetic method for the preparation of novel NSAID twin esters 6a-i containing amino a...
Various amide-based prodrugs of sulphonamides have been synthesised by condensing appropriate sulpho...
The aim of the work. Development of methods for obtaining new morpholin-4-yl-2-thioxoacetamides and ...
β-Amino-α-ketoamides 1 are a class of compounds exhibiting biological activity as reversible covalen...
In the present study, five derivatives have been designed to be synthesized as possible mutual prodr...
There will always be a need for new pharmaceuticals as long as there are those that will be around t...
International audienceA series of substituted 6-nitrophenylpropanamide derivatives (1-20) were synth...
Synthesis of a series of new ketoprofenamides (3a-h) is described. Amide formation was achieved by a...
Synthesis of a series of new ketoprofenamides (3a-h) is described. Amide formation was achieved by a...
Synthesis of a series of new ketoprofenamides (3a-h) is described. Amide formation was achieved by a...
A series of novel ketoprofen derivatives 4a-j bearing both amide and carbamate functionalities were ...
The carboxylic acid groups of (S) ketoprofen and (S) ibuprofen were brought into reaction with subst...
A convenient synthetic method for the preparation of novel NSAID twin esters 6a-i containing amino a...
PubMedID: 8876939The synthesis of amide prodrugs of some 2-arylpropionic acids (ibuprofen, naproxen,...
A Series Of Potential Biologically Active Compounds Have Been Synthesized Through The Derivatization...
A convenient synthetic method for the preparation of novel NSAID twin esters 6a-i containing amino a...
Various amide-based prodrugs of sulphonamides have been synthesised by condensing appropriate sulpho...
The aim of the work. Development of methods for obtaining new morpholin-4-yl-2-thioxoacetamides and ...
β-Amino-α-ketoamides 1 are a class of compounds exhibiting biological activity as reversible covalen...
In the present study, five derivatives have been designed to be synthesized as possible mutual prodr...
There will always be a need for new pharmaceuticals as long as there are those that will be around t...
International audienceA series of substituted 6-nitrophenylpropanamide derivatives (1-20) were synth...