Exciting new results from a genetic study in humans and functional studies in mice have pinpointed interleukin 23 (IL23) and its receptor as a key pathway in the pathogenesis of inflammatory bowel disease (IBD). These findings reveal a hitherto unappreciated role for the IL23 axis in intestinal inflammation and may open new avenues for development of therapeutic strategies in IBD
Genome-wide association studies (GWAS) in several populations have demonstrated significant associat...
Genome-wide association studies as well as murine models have shown that the interleukin 23 recepto...
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract. In...
The IL-23 cytokine, derived predominantly from macrophages and dendritic cells in response to microb...
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract in...
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract in...
Although the precise aetiology of inflammatory bowel disease (IBD) remains unclear, recent discoveri...
Although the precise aetiology of inflammatory bowel disease (IBD) remains unclear, recent discoveri...
Immune responses in the intestine are tightly regulated to ensure host protective immunity in the ab...
Immune responses in the intestine are tightly regulated to ensure host protective immunity in the ab...
The aetiology of IBD is unknown, but available evidence suggests that an aberrant immune response to...
SummaryMutations in the IL23R gene are linked to inflammatory bowel disease susceptibility. Experime...
The CD40-CD154 pathway is important in the pathogenesis of inflammatory bowel disease. Here we show ...
Mutations in the IL23R gene are linked to inflammatory bowel disease susceptibility. Experimental mo...
Genome-wide association studies (GWAS) in several populations have demonstrated significant associat...
Genome-wide association studies (GWAS) in several populations have demonstrated significant associat...
Genome-wide association studies as well as murine models have shown that the interleukin 23 recepto...
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract. In...
The IL-23 cytokine, derived predominantly from macrophages and dendritic cells in response to microb...
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract in...
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract in...
Although the precise aetiology of inflammatory bowel disease (IBD) remains unclear, recent discoveri...
Although the precise aetiology of inflammatory bowel disease (IBD) remains unclear, recent discoveri...
Immune responses in the intestine are tightly regulated to ensure host protective immunity in the ab...
Immune responses in the intestine are tightly regulated to ensure host protective immunity in the ab...
The aetiology of IBD is unknown, but available evidence suggests that an aberrant immune response to...
SummaryMutations in the IL23R gene are linked to inflammatory bowel disease susceptibility. Experime...
The CD40-CD154 pathway is important in the pathogenesis of inflammatory bowel disease. Here we show ...
Mutations in the IL23R gene are linked to inflammatory bowel disease susceptibility. Experimental mo...
Genome-wide association studies (GWAS) in several populations have demonstrated significant associat...
Genome-wide association studies (GWAS) in several populations have demonstrated significant associat...
Genome-wide association studies as well as murine models have shown that the interleukin 23 recepto...
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract. In...
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