Objective Neuromyelitis optica (NMO) is a rare antibody-mediated CNS disease characterised by disabling relapses leading to high morbidity and mortality. Understanding relapse activity and severity is important for treatment decisions and clinical trial design. We assessed (1) whether clinical and demographic factors associate with different relapse rates and (2) the relative impact of immunosuppressive treatments on relapse rates and on attack-related residual disability. Methods Clinical, demographic and treatment data were prospectively collected from 79 consecutive aquaporin 4 antibody positive patients seen in the nationally commissioned Oxford NMO service. The influence of clinical features on annualised relapse rates (using multiple ...
<p>Data shown as median and range (minimum, maximum). EDSS, Kurtzke Expanded Disability Status Scale...
Introduction: Neuromyelitis optica spectrum disorder (NMOSD) is a neuroinflammatory disorder of the ...
PubMed ID: 26468870Background: Neuromyelitis optica (NMO) is an immune-mediated, chronic relapsing, ...
Objective Neuromyelitis optica (NMO) is a rare antibody-mediated CNS disease characterised by disabl...
Objective Neuromyelitis optica (NMO) is a rare antibody-mediated CNS disease characterised by disabl...
IMPORTANCE: Neuromyelitis optica (NMO) is an inflammatory disease of the optic nerves and spinal cor...
The comparative clinical and demographic features of neuromyelitis optica (NMO) are not well known. ...
The comparative clinical and demographic features of neuromyelitis optica (NMO) are not well known. ...
Objective To analyse predictors for relapses and number of attacks under different immunotherapies i...
Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune inflammatory disorder of the cen...
Objective: Neuromyelitis optica (NMO) attacks are often severe, difficult to treat, and leave residu...
ObjectiveNeuromyelitis optica (NMO) attacks often are severe, are difficult to treat, and leave resi...
Background: Aquaporin-4-IgG positive (AQP4-IgG(+)) Neuromyelitis Optica Spectrum Disorder (NMOSD) is...
Background: Aquaporin-4-IgG positive (AQP4-IgG+) Neuromyelitis Optica Spectrum Disorder (NMOSD) is a...
Pathogenic antibodies targeting the aquaporin-4 water channel on astrocytes are associated with rela...
<p>Data shown as median and range (minimum, maximum). EDSS, Kurtzke Expanded Disability Status Scale...
Introduction: Neuromyelitis optica spectrum disorder (NMOSD) is a neuroinflammatory disorder of the ...
PubMed ID: 26468870Background: Neuromyelitis optica (NMO) is an immune-mediated, chronic relapsing, ...
Objective Neuromyelitis optica (NMO) is a rare antibody-mediated CNS disease characterised by disabl...
Objective Neuromyelitis optica (NMO) is a rare antibody-mediated CNS disease characterised by disabl...
IMPORTANCE: Neuromyelitis optica (NMO) is an inflammatory disease of the optic nerves and spinal cor...
The comparative clinical and demographic features of neuromyelitis optica (NMO) are not well known. ...
The comparative clinical and demographic features of neuromyelitis optica (NMO) are not well known. ...
Objective To analyse predictors for relapses and number of attacks under different immunotherapies i...
Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune inflammatory disorder of the cen...
Objective: Neuromyelitis optica (NMO) attacks are often severe, difficult to treat, and leave residu...
ObjectiveNeuromyelitis optica (NMO) attacks often are severe, are difficult to treat, and leave resi...
Background: Aquaporin-4-IgG positive (AQP4-IgG(+)) Neuromyelitis Optica Spectrum Disorder (NMOSD) is...
Background: Aquaporin-4-IgG positive (AQP4-IgG+) Neuromyelitis Optica Spectrum Disorder (NMOSD) is a...
Pathogenic antibodies targeting the aquaporin-4 water channel on astrocytes are associated with rela...
<p>Data shown as median and range (minimum, maximum). EDSS, Kurtzke Expanded Disability Status Scale...
Introduction: Neuromyelitis optica spectrum disorder (NMOSD) is a neuroinflammatory disorder of the ...
PubMed ID: 26468870Background: Neuromyelitis optica (NMO) is an immune-mediated, chronic relapsing, ...