Catalytic enantio- and diastereoselective Mannich reaction of α-substituted isocyanoacetates and ketimines.

de la Campa, R
Gammack Yamagata, AD
Ortín, I
Franchino, A
Thompson, AL
Odell, B
Dixon, Darren

Publication date

August 2016

DOI

10.1039/c6cc04132a

Publisher

Royal Society of Chemistry (RSC)

Journal

Chemical Communications

Abstract

The highly diastereo- and enantioselective Mannich addition/cyclisation reaction of α-substituted isocyanoacetate ester pronucleophiles and (hetero)aryl and alkyl methyl ketone-derived ketimines using a silver acetate and a cinchona-derived amino phosphine binary catalyst system is reported

Extracted data

We use cookies to provide a better user experience.

Data Protection

Catalytic enantio- and diastereoselective Mannich reaction of α-substituted isocyanoacetates and ketimines.

Abstract

Extracted data

Catalytic enantio- and diastereoselective Mannich reaction of α-substituted isocyanoacetates and ketimines.

Abstract

Extracted data

Related items

Related items