Highly diastereoselective reductions and organometallic additions in bicyclic lactams have been observed, which appear to result either from a stereoelectronic interaction of the pyramidalised nitrogen lone pair or from steric interactions in the bicyclic system. These products can be readily deprotected to give hydroxylated lactams
We report that the stereochemical outcome of the conjugate addition of organocopper reagents to bicy...
We report that the stereochemical outcome of the conjugate addition of organocopper reagents to bicy...
Most known methods to access delta-lactams with stereogenic centers at the alpha- and beta-positions...
Highly diastereoselective reductions and organometallic additions in bicyclic lactams have been obse...
The synthesis and alkylation of [4.3.0]-bicyclic lactams, derived from 6-oxopipecolic acid, have bee...
The synthesis and alkylation of [4.3.0]-bicyclic lactams, derived from 6-oxopipecolic acid, have bee...
Previously reported experimental results indicate that photooxygenation of homochiral N-(hydroxyalky...
Previously reported experimental results indicate that photooxygenation of homochiral N-(hydroxyalky...
Previously reported experimental results indicate that photooxygenation of homochiral N-(hydroxyalky...
The synthesis of substituted [4.3.0] bicyclic lactams derived from 6- oxo-2-hydroxymethylpiperidine ...
We report that the stereochemical outcome of the conjugate addition of organocopper reagents to bicy...
We report that the stereochemical outcome of the conjugate addition of organocopper reagents to bicy...
We report that the stereochemical outcome of the conjugate addition of organocopper reagents to bicy...
We report that the stereochemical outcome of the conjugate addition of organocopper reagents to bicy...
We report that the stereochemical outcome of the conjugate addition of organocopper reagents to bicy...
We report that the stereochemical outcome of the conjugate addition of organocopper reagents to bicy...
We report that the stereochemical outcome of the conjugate addition of organocopper reagents to bicy...
Most known methods to access delta-lactams with stereogenic centers at the alpha- and beta-positions...
Highly diastereoselective reductions and organometallic additions in bicyclic lactams have been obse...
The synthesis and alkylation of [4.3.0]-bicyclic lactams, derived from 6-oxopipecolic acid, have bee...
The synthesis and alkylation of [4.3.0]-bicyclic lactams, derived from 6-oxopipecolic acid, have bee...
Previously reported experimental results indicate that photooxygenation of homochiral N-(hydroxyalky...
Previously reported experimental results indicate that photooxygenation of homochiral N-(hydroxyalky...
Previously reported experimental results indicate that photooxygenation of homochiral N-(hydroxyalky...
The synthesis of substituted [4.3.0] bicyclic lactams derived from 6- oxo-2-hydroxymethylpiperidine ...
We report that the stereochemical outcome of the conjugate addition of organocopper reagents to bicy...
We report that the stereochemical outcome of the conjugate addition of organocopper reagents to bicy...
We report that the stereochemical outcome of the conjugate addition of organocopper reagents to bicy...
We report that the stereochemical outcome of the conjugate addition of organocopper reagents to bicy...
We report that the stereochemical outcome of the conjugate addition of organocopper reagents to bicy...
We report that the stereochemical outcome of the conjugate addition of organocopper reagents to bicy...
We report that the stereochemical outcome of the conjugate addition of organocopper reagents to bicy...
Most known methods to access delta-lactams with stereogenic centers at the alpha- and beta-positions...