OBJECTIVE: It has been suggested that patients with acromegaly may be at risk of developing colorectal carcinoma. In order to clarify this issue, we have evaluated the prevalence of carcinoma, premalignant tubulovillous adenomas and hyperplastic colonic polyps in a large cohort of patients with acromegaly. DESIGN: Prospective colonoscopic examination by a single operator. PATIENTS: One hundred and twenty-nine patients with biochemically proven acromegaly. RESULTS: At least one lesion was visualized in 63 patients. Adenocarcinoma was present in six patients (5%), but only two had symptoms; all lesions were endoscopically obvious. Compared with a normal group, the odds ratio of colorectal cancer is increased at 13.5 (95% confidence intervals ...
The prevalence of colon polyposis andmalignancies is increased in acromegalic patients as compared t...
Patients with acromegaly are at increased risk of colorectal neoplasia and, by analogy with high-ris...
The high prevalence of colonic polyps in acromegalic patients is well known. Colonic adenomatous pol...
Background: Patients with acromegaly are reported to have a higher prevalence of colorectal adenoma,...
An increase in the prevalence of colorectal polyps and cancer is reported in patients with acromegal...
Patients with acromegaly are reported to be at risk of developing adenomatous colonic polyps, which ...
Acromegaly is an infrequent disease attributable to endogenous excess of GH and IGF-I. Human studies...
Acromegaly is an infrequent disease attributable to endogenous excess of GH and IGF-I. Human studies...
OBJECTIVE: It is suggested that patients with acromegaly have an increased risk of colorectal cancer...
Acromegaly seems to be associated with an increased prevalence of colonic adenomas, although factors...
Seventeen patients with acromegaly were prospectively studied with barium enemas and colonoscopy to ...
CONTEXT: Hyperinsulinemia is associated with colon carcinoma in the general population. Patients wit...
OBJECTIVE: The balance of evidence suggests that acromegaly is a risk factor for colonic neoplasia. ...
Acromegalic patients have an increased risk for the development of colorectal cancer. For this reaso...
Introduction The prevalence of colonic polyps and cancer in patients with acromegaly group has remai...
The prevalence of colon polyposis andmalignancies is increased in acromegalic patients as compared t...
Patients with acromegaly are at increased risk of colorectal neoplasia and, by analogy with high-ris...
The high prevalence of colonic polyps in acromegalic patients is well known. Colonic adenomatous pol...
Background: Patients with acromegaly are reported to have a higher prevalence of colorectal adenoma,...
An increase in the prevalence of colorectal polyps and cancer is reported in patients with acromegal...
Patients with acromegaly are reported to be at risk of developing adenomatous colonic polyps, which ...
Acromegaly is an infrequent disease attributable to endogenous excess of GH and IGF-I. Human studies...
Acromegaly is an infrequent disease attributable to endogenous excess of GH and IGF-I. Human studies...
OBJECTIVE: It is suggested that patients with acromegaly have an increased risk of colorectal cancer...
Acromegaly seems to be associated with an increased prevalence of colonic adenomas, although factors...
Seventeen patients with acromegaly were prospectively studied with barium enemas and colonoscopy to ...
CONTEXT: Hyperinsulinemia is associated with colon carcinoma in the general population. Patients wit...
OBJECTIVE: The balance of evidence suggests that acromegaly is a risk factor for colonic neoplasia. ...
Acromegalic patients have an increased risk for the development of colorectal cancer. For this reaso...
Introduction The prevalence of colonic polyps and cancer in patients with acromegaly group has remai...
The prevalence of colon polyposis andmalignancies is increased in acromegalic patients as compared t...
Patients with acromegaly are at increased risk of colorectal neoplasia and, by analogy with high-ris...
The high prevalence of colonic polyps in acromegalic patients is well known. Colonic adenomatous pol...